Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetThyroid hormone receptor beta(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL

LigandBDBM50148672(4-(2-(pyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]p...)Copy SMILESCopy InChI

Affinity DataIC50:  104nMAssay Description:Inhibitory activity against TGF-beta type I receptorMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetTGF-beta receptor type-1(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL

LigandBDBM50148672(4-(2-(pyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]p...)Copy SMILESCopy InChI

Affinity DataIC50:  104nMAssay Description:Inhibition of TGFR1More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathway
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL

LigandBDBM50148672(4-(2-(pyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]p...)Copy SMILESCopy InChI

Affinity DataIC50:  7.90E+3nMAssay Description:Inhibitory activity against Mitogen-activated protein kinase p38More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI