Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 202 hits in this display
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM86689(CAS_84371-65-3 | NSC_55245 | RU-486)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM86689(CAS_84371-65-3 | NSC_55245 | RU-486)
BDBM86689(CAS_84371-65-3 | NSC_55245 | RU-486)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM50072024((11R,13S,14S,17S)-11-(4-Dimethylamino-phenyl)-17-h...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
Ki: 6nMAssay Description:Displacement of [3H]-dexamethasone from cytosolic fraction of human recombinant glucocorticoid receptor by scintillation counting analysisMore data for this Ligand-Target Pair
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
Ki: 15nMAssay Description:Displacement of [3H]-progesterone from cytosolic fraction of human recombinant progesterone-B receptor by scintillation counting analysisMore data for this Ligand-Target Pair
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM86689(CAS_84371-65-3 | NSC_55245 | RU-486)
BDBM86689(CAS_84371-65-3 | NSC_55245 | RU-486)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM86689(CAS_84371-65-3 | NSC_55245 | RU-486)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM86689(CAS_84371-65-3 | NSC_55245 | RU-486)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM86689(CAS_84371-65-3 | NSC_55245 | RU-486)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
IC50: 0.0250nMAssay Description:In vitro antagonist potency in transactivation assay in neuroblastoma cells expressing human PR-B progesterone receptorMore data for this Ligand-Target Pair
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
IC50: 0.0280nMAssay Description:In vitro antgonist potency in transactivation assay in neuroblastoma cells expressing human PR-A progesterone receptorMore data for this Ligand-Target Pair
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
IC50: 0.0500nMAssay Description:Antiprogestagenic activity at progesterone receptor in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activityMore data for this Ligand-Target Pair
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
IC50: 0.0730nMAssay Description:Antagonist activity at PR in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity measured after 24 hrsMore data for this Ligand-Target Pair
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
IC50: 0.130nMAssay Description:Antagonist activity against progesterone receptor (PR) in an alkaline phosphatase assay in the T47D human breast carcinoma cell lineMore data for this Ligand-Target Pair
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
IC50: 0.180nMAssay Description:Concentration required to give half-maximal inhibition against human Progesterone receptor B isoform in co-transfected CV-1 cell lines.More data for this Ligand-Target Pair
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
IC50: 0.200nMAssay Description:Antagonist activity at progesterone receptor assessed as progesterone-induced alkaline phosphatase activity in human T47D cellsMore data for this Ligand-Target Pair
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
IC50: 0.200nMAssay Description:Antagonist activity at progesterone receptor in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activityMore data for this Ligand-Target Pair
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
IC50: 0.200nMAssay Description:Antagonist activity at human PR expressed in human T47D cells assessed as inhibition of progesterone induced alkaline phosphataseMore data for this Ligand-Target Pair
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
IC50: 0.200nMAssay Description:Inhibitory concentration against progesterone stimulated alkaline phosphatase activity in T47D human breast carcinoma cell lineMore data for this Ligand-Target Pair
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
IC50: 0.200nMAssay Description:Antagonistic activity against Progesterone receptor (PR) in transcriptional activation assay in human T47D breast carcinoma cell lineMore data for this Ligand-Target Pair
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
IC50: 0.25nMAssay Description:Antagonist activity against PR beta-mediated transactivation of MMTV luciferase reporter gene in BacMam transduced progesterone-stimulated CV1 cellsMore data for this Ligand-Target Pair
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
IC50: 0.298nMAssay Description:Antagonist activity against glucocorticoid receptor (unknown origin) expressed in HEK293 cells by GRE-dependent luciferase reporter gene assayMore data for this Ligand-Target Pair
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
IC50: 0.300nMAssay Description:Inhibitory concentration for antagonistic activity towards human progesterone receptor (hPR) using the cotransfection assay in CV-1 cellsMore data for this Ligand-Target Pair
BDBM50072024((11R,13S,14S,17S)-11-(4-Dimethylamino-phenyl)-17-h...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
IC50: 0.600nMAssay Description:Antagonist activity at human GR ligand binding domain expressed in african green monkey COS7 cells in presence of Dexamethasone by Gal4 hybrid assayMore data for this Ligand-Target Pair
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
IC50: 1.40nMAssay Description:Antagonist activity at progesterone receptor in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activityMore data for this Ligand-Target Pair
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
IC50: 1.40nMAssay Description:Antagonist activity at human progesterone receptor assessed as inhibition of alkaline phosphatase activity in human T47D cellsMore data for this Ligand-Target Pair
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
IC50: 1.40nMAssay Description:Antagonist activity at progesterone receptor in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activityMore data for this Ligand-Target Pair
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
IC50: 2.60nMAssay Description:Antagonist activity at progesterone receptor expressed in human T47 cells assessed as blockade of progesterone-induced alkaline phosphatase activityMore data for this Ligand-Target Pair
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
IC50: 2.90nMpH: 8.0 T: 2°CAssay Description:For compounds able to displace the radiolabeled ligand (competitor) from the receptor an IC50 value (the concentration required to inhibit 50% of the...More data for this Ligand-Target Pair
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
IC50: 4.70nMAssay Description:Activity at GR assessed as ability to antagonize dexamethasone-induced MMTV luciferase reporter gene transactivation in human A549 cellsChecked by AuthorMore data for this Ligand-Target Pair
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
IC50: 5nMAssay Description:Activity at GR expressed in CHO cells assessed as decrease in dexamethasone-stimulated alkaline phosphatase production by GRAF assayMore data for this Ligand-Target Pair
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
IC50: 6.90nMAssay Description:Antagonist activity at cloned androgen receptor-ligand binding domain expressed in african green monkey COS7 cells by two hybrid luciferase assayMore data for this Ligand-Target Pair
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
IC50: 8.70nMAssay Description:Displacement of fluormone RED from human full length glucocorticoid receptor after 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
IC50: 8.80nMpH: 8.0 T: 2°CAssay Description:For compounds able to displace the radiolabeled ligand (competitor) from the receptor an IC50 value (the concentration required to inhibit 50% of the...More data for this Ligand-Target Pair
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
IC50: 11nMAssay Description:Antagonist activity at GR in mini pig PBMC assessed as reduction in dexamethasone-induced GILZ gene expression incubated for 24 hrs by RT-qPCR methodMore data for this Ligand-Target Pair
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
IC50: 13nMAssay Description:Antagonist activity at GR in human OVCAR5 assessed as reduction in dexamethasone-induced FKBP5 gene expression incubated for 24 hrs by RT-qPCR methodMore data for this Ligand-Target Pair
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
IC50: 15nMAssay Description:Antagonist activity at GR in human PBMC assessed as reduction in dexamethasone-induced FKBP5 gene expression incubated for 6 hrs by RT-qPCR methodMore data for this Ligand-Target Pair
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
IC50: 18nMAssay Description:Antagonist activity at GR in human PBMC assessed as reduction in dexamethasone-induced GILZ gene expression incubated for 6 hrs by RT-qPCR methodMore data for this Ligand-Target Pair
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
IC50: 20nMAssay Description:Antagonist activity at GR in dog PBMC assessed as reduction in dexamethasone-induced FKBP5 gene expression incubated for 6 hrs by RT-qPCR methodMore data for this Ligand-Target Pair
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
IC50: 33nMAssay Description:Antagonist activity at GR in dog PBMC assessed as reduction in dexamethasone-induced GILZ gene expression incubated for 6 hrs by RT-qPCR methodMore data for this Ligand-Target Pair
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
IC50: <1.00E+3nMAssay Description:Agonist activity at GR assessed as NF-kappaB-mediated transrepression of secreted placental alkaline phosphatase gene in human A549 cellsChecked by AuthorMore data for this Ligand-Target Pair
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
IC50: 6.00E+3nMpH: 8.0 T: 2°CAssay Description:For compounds able to displace the radiolabeled ligand (competitor) from the receptor an IC50 value (the concentration required to inhibit 50% of the...More data for this Ligand-Target Pair
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
Kd: 2.00E+4nMAssay Description:Compound was tested for the binding affinity towards recombinant NBD2 C-terminal cytotoxic nucleotide-binding domain of mouse P-GlycoproteinMore data for this Ligand-Target Pair
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
EC50: 12nMAssay Description:Agonist activity at AR (unknown origin) expressed in human LNCaP cells incubated for 20 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
BDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
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