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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
22
hits in this display
Target
Disintegrin and metalloproteinase domain-containing protein 17
(Homo sapiens (Human))
The M. S. University Of Baroda
Curated by
ChEMBL
Ligand
BDBM23500
(4-({[4-(but-2-yn-1-yloxy)benzene]sulfonyl}methyl)-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.5nM
Assay Description:
Inhibition of TACE
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Disintegrin and metalloproteinase domain-containing protein 17
(Homo sapiens (Human))
The M. S. University Of Baroda
Curated by
ChEMBL
Ligand
BDBM23500
(4-({[4-(but-2-yn-1-yloxy)benzene]sulfonyl}methyl)-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.5nM
Assay Description:
Inhibition of TACE in human whole blood assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Disintegrin and metalloproteinase domain-containing protein 17
(Homo sapiens (Human))
The M. S. University Of Baroda
Curated by
ChEMBL
Ligand
BDBM23500
(4-({[4-(but-2-yn-1-yloxy)benzene]sulfonyl}methyl)-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.5nM
Assay Description:
Inhibition of TACE by FRET assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Disintegrin and metalloproteinase domain-containing protein 17
(Homo sapiens (Human))
The M. S. University Of Baroda
Curated by
ChEMBL
Ligand
BDBM23500
(4-({[4-(but-2-yn-1-yloxy)benzene]sulfonyl}methyl)-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.5nM
Assay Description:
Inhibition of TACE
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Disintegrin and metalloproteinase domain-containing protein 17
(Homo sapiens (Human))
The M. S. University Of Baroda
Curated by
ChEMBL
Ligand
BDBM23500
(4-({[4-(but-2-yn-1-yloxy)benzene]sulfonyl}methyl)-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3nM
pH: 7.4 T: 2°C
Assay Description:
Compounds were tested for their ability to inhibit the cleavage of the substrate by the purified enzyme in a fluorescence-based fluorescence resonanc...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Collagenase 3
(Homo sapiens (Human))
Wyeth Research
Ligand
BDBM23500
(4-({[4-(but-2-yn-1-yloxy)benzene]sulfonyl}methyl)-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 157nM
T: 2°C
Assay Description:
A continuous assay was used in which the substrate is a synthetic peptide containing a fluorescent group (7-methoxycoumarin), which is quenched by en...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Collagenase 3
(Homo sapiens (Human))
Wyeth Research
Ligand
BDBM23500
(4-({[4-(but-2-yn-1-yloxy)benzene]sulfonyl}methyl)-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 230nM
Assay Description:
Inhibition of MMP13
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Collagenase 3
(Homo sapiens (Human))
Wyeth Research
Ligand
BDBM23500
(4-({[4-(but-2-yn-1-yloxy)benzene]sulfonyl}methyl)-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 230nM
Assay Description:
Inhibition of MMP13
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Collagenase 3
(Homo sapiens (Human))
Wyeth Research
Ligand
BDBM23500
(4-({[4-(but-2-yn-1-yloxy)benzene]sulfonyl}methyl)-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 230nM
Assay Description:
Inhibition of MMP13
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
72 kDa type IV collagenase
(Homo sapiens (Human))
Wyeth Research
Ligand
BDBM23500
(4-({[4-(but-2-yn-1-yloxy)benzene]sulfonyl}methyl)-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 280nM
pH: 7.4 T: 2°C
Assay Description:
A continuous assay was used in which the substrate is a synthetic peptide containing a fluorescent group (7-methoxycoumarin), which is quenched by en...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
72 kDa type IV collagenase
(Homo sapiens (Human))
Wyeth Research
Ligand
BDBM23500
(4-({[4-(but-2-yn-1-yloxy)benzene]sulfonyl}methyl)-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 355nM
Assay Description:
Inhibition of MMP2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
72 kDa type IV collagenase
(Homo sapiens (Human))
Wyeth Research
Ligand
BDBM23500
(4-({[4-(but-2-yn-1-yloxy)benzene]sulfonyl}methyl)-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 355nM
Assay Description:
Inhibition of MMP2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
72 kDa type IV collagenase
(Homo sapiens (Human))
Wyeth Research
Ligand
BDBM23500
(4-({[4-(but-2-yn-1-yloxy)benzene]sulfonyl}methyl)-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 355nM
Assay Description:
Inhibition of MMP2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Matrix metalloproteinase-9
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM23500
(4-({[4-(but-2-yn-1-yloxy)benzene]sulfonyl}methyl)-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.67E+3nM
Assay Description:
Inhibition of MMP9
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Matrix metalloproteinase-9
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM23500
(4-({[4-(but-2-yn-1-yloxy)benzene]sulfonyl}methyl)-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.67E+3nM
Assay Description:
Inhibition of MMP9
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Matrix metalloproteinase-9
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM23500
(4-({[4-(but-2-yn-1-yloxy)benzene]sulfonyl}methyl)-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.67E+3nM
Assay Description:
Inhibition of MMP9
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Matrix metalloproteinase-14
(Homo sapiens (Human))
Wyeth Research
Ligand
BDBM23500
(4-({[4-(but-2-yn-1-yloxy)benzene]sulfonyl}methyl)-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3.64E+3nM
T: 2°C
Assay Description:
A continuous assay was used in which the substrate is a synthetic peptide containing a fluorescent group (7-methoxycoumarin), which is quenched by en...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Matrix metalloproteinase-14
(Homo sapiens (Human))
Wyeth Research
Ligand
BDBM23500
(4-({[4-(but-2-yn-1-yloxy)benzene]sulfonyl}methyl)-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 4.71E+3nM
Assay Description:
Inhibition of MMP14
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Matrix metalloproteinase-14
(Homo sapiens (Human))
Wyeth Research
Ligand
BDBM23500
(4-({[4-(but-2-yn-1-yloxy)benzene]sulfonyl}methyl)-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 4.71E+3nM
Assay Description:
Inhibition of MMP14
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Interstitial collagenase
(Homo sapiens (Human))
University Of Athens
Curated by
ChEMBL
Ligand
BDBM23500
(4-({[4-(but-2-yn-1-yloxy)benzene]sulfonyl}methyl)-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 8.78E+3nM
Assay Description:
Inhibition of MMP1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Interstitial collagenase
(Homo sapiens (Human))
University Of Athens
Curated by
ChEMBL
Ligand
BDBM23500
(4-({[4-(but-2-yn-1-yloxy)benzene]sulfonyl}methyl)-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 8.78E+3nM
Assay Description:
Inhibition of MMP1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Interstitial collagenase
(Homo sapiens (Human))
University Of Athens
Curated by
ChEMBL
Ligand
BDBM23500
(4-({[4-(but-2-yn-1-yloxy)benzene]sulfonyl}methyl)-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 8.78E+3nM
Assay Description:
Inhibition of MMP1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI