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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 20 hits in this display   

TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University Of Utah

Curated by ChEMBL
LigandPNGBDBM50445346(CHEMBL3104250)
Affinity DataKi:  14nMAssay Description:Non-competitive inhibition of recombinant full-length His6-tagged LSD1 (unknown origin) using dimethylated K4N-terminal H3 peptide as substrate at 1 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University Of Utah

Curated by ChEMBL
LigandPNGBDBM50445346(CHEMBL3104250)
Affinity DataKi:  32nMAssay Description:Non-competitive inhibition of recombinant full-length His6-tagged LSD1 (unknown origin) using dimethylated K4N-terminal H3 peptide as substrate at 10...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University Of Utah

Curated by ChEMBL
LigandPNGBDBM50445346(CHEMBL3104250)
Affinity DataKi:  35nMAssay Description:Non-competitive inhibition of recombinant full-length His6-tagged LSD1 (unknown origin) using dimethylated K4N-terminal H3 peptide as substrate at 3 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University Of Utah

Curated by ChEMBL
LigandPNGBDBM50445346(CHEMBL3104250)
Affinity DataKi:  35nMAssay Description:Non-competitive inhibition of recombinant full-length His6-tagged LSD1 (unknown origin) using dimethylated K4N-terminal H3 peptide as substrate at 30...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University Of Utah

Curated by ChEMBL
LigandPNGBDBM50445346(CHEMBL3104250)
Affinity DataKi:  55nMAssay Description:Non-competitive inhibition of recombinant full-length His6-tagged LSD1 (unknown origin) using dimethylated K4N-terminal H3 peptide as substrate at 10...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University Of Utah

Curated by ChEMBL
LigandPNGBDBM151611(SP-2509 | US11433053, Example HCI-2509 | US8987335...)
Affinity DataIC50:  11nMpH: 7.5 T: 2°CAssay Description:The LSD1 screening biochemical assay was performed by Shanghai ChemPartner Co. Ltd and the detailed protocol was shown as followed. The AlphaLISA ass...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University Of Utah

Curated by ChEMBL
LigandPNGBDBM151611(SP-2509 | US11433053, Example HCI-2509 | US8987335...)
Affinity DataIC50:  13nMAssay Description:The primary assay for compound inhibitory activity was the LSD1 Inhibitor Screening Assay Kit (Cayman Chemical Company, Ann Arbor, Mich.; Cayman Chem...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University Of Utah

Curated by ChEMBL
LigandPNGBDBM50445346(CHEMBL3104250)
Affinity DataIC50:  13nMAssay Description:Inhibition of LSD1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University Of Utah

Curated by ChEMBL
LigandPNGBDBM151611(SP-2509 | US11433053, Example HCI-2509 | US8987335...)
Affinity DataIC50:  13nMAssay Description:The primary assay for compound inhibitory activity was the LSD1 Inhibitor Screening Assay Kit (Cayman Chemical Company, Ann Arbor, Mich.; Cayman Chem...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University Of Utah

Curated by ChEMBL
LigandPNGBDBM50445346(CHEMBL3104250)
Affinity DataIC50:  13nMAssay Description:Inhibition of LSD1 (unknown origin) using dimethyl K4 peptide as substrate assessed as resorufin level by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University Of Utah

Curated by ChEMBL
LigandPNGBDBM50445346(CHEMBL3104250)
Affinity DataIC50:  24nMAssay Description:Inhibition of recombinant LSD1 (unknown origin) using H3K4me2 as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University Of Utah

Curated by ChEMBL
LigandPNGBDBM151611(SP-2509 | US11433053, Example HCI-2509 | US8987335...)
Affinity DataIC50: <50nMAssay Description:The purpose of this test is to test the in vitro inhibitory activities of the compounds against LSD1. The enzyme used in this experiment was human LS...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 2C9(Homo sapiens (Human))
University Of Utah

Curated by ChEMBL
LigandPNGBDBM50445346(CHEMBL3104250)
Affinity DataIC50:  8.04E+3nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
University Of Utah

Curated by ChEMBL
LigandPNGBDBM50445346(CHEMBL3104250)
Affinity DataIC50:  9.76E+3nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
University Of Utah

Curated by ChEMBL
LigandPNGBDBM50445346(CHEMBL3104250)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
University Of Utah

Curated by ChEMBL
LigandPNGBDBM50445346(CHEMBL3104250)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
University Of Utah Research Foundation

US Patent
LigandPNGBDBM151611(SP-2509 | US11433053, Example HCI-2509 | US8987335...)
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of monoamine oxidase activity was carried used using the MAO-Glo.TM. Assay Kit according to the manufacturer's suggested protocol. Bri...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
University Of Utah Research Foundation

US Patent
LigandPNGBDBM151611(SP-2509 | US11433053, Example HCI-2509 | US8987335...)
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of monoamine oxidase activity was carried used using the MAO-GIo Assay Kit according to the manufacturer's suggested protocol. Briefly...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
University Of Utah Research Foundation

US Patent
LigandPNGBDBM151611(SP-2509 | US11433053, Example HCI-2509 | US8987335...)
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of monoamine oxidase activity was carried used using the MAO-Glo.TM. Assay Kit according to the manufacturer's suggested protocol. Bri...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
University Of Utah Research Foundation

US Patent
LigandPNGBDBM151611(SP-2509 | US11433053, Example HCI-2509 | US8987335...)
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of monoamine oxidase activity was carried used using the MAO-GIo Assay Kit according to the manufacturer's suggested protocol. Briefly...More data for this Ligand-Target Pair
In DepthDetails US Patent