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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
20
hits in this display
Target
Lysine-specific histone demethylase 1A
(Homo sapiens (Human))
University Of Utah
Curated by
ChEMBL
Ligand
BDBM50445346
(CHEMBL3104250)
Copy SMILES
Copy InChI
Affinity Data
Ki: 14nM
Assay Description:
Non-competitive inhibition of recombinant full-length His6-tagged LSD1 (unknown origin) using dimethylated K4N-terminal H3 peptide as substrate at 1 ...
More data for this Ligand-Target Pair
Target Info
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MMDB
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KEGG
UniProtKB/SwissProt
B.MOAD
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Target
Lysine-specific histone demethylase 1A
(Homo sapiens (Human))
University Of Utah
Curated by
ChEMBL
Ligand
BDBM50445346
(CHEMBL3104250)
Copy SMILES
Copy InChI
Affinity Data
Ki: 32nM
Assay Description:
Non-competitive inhibition of recombinant full-length His6-tagged LSD1 (unknown origin) using dimethylated K4N-terminal H3 peptide as substrate at 10...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
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Target
Lysine-specific histone demethylase 1A
(Homo sapiens (Human))
University Of Utah
Curated by
ChEMBL
Ligand
BDBM50445346
(CHEMBL3104250)
Copy SMILES
Copy InChI
Affinity Data
Ki: 35nM
Assay Description:
Non-competitive inhibition of recombinant full-length His6-tagged LSD1 (unknown origin) using dimethylated K4N-terminal H3 peptide as substrate at 3 ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
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CHEMBL
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Article
PubMed
Copy BDB DOI
Target
Lysine-specific histone demethylase 1A
(Homo sapiens (Human))
University Of Utah
Curated by
ChEMBL
Ligand
BDBM50445346
(CHEMBL3104250)
Copy SMILES
Copy InChI
Affinity Data
Ki: 35nM
Assay Description:
Non-competitive inhibition of recombinant full-length His6-tagged LSD1 (unknown origin) using dimethylated K4N-terminal H3 peptide as substrate at 30...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Similars
In Depth
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Article
PubMed
Copy BDB DOI
Target
Lysine-specific histone demethylase 1A
(Homo sapiens (Human))
University Of Utah
Curated by
ChEMBL
Ligand
BDBM50445346
(CHEMBL3104250)
Copy SMILES
Copy InChI
Affinity Data
Ki: 55nM
Assay Description:
Non-competitive inhibition of recombinant full-length His6-tagged LSD1 (unknown origin) using dimethylated K4N-terminal H3 peptide as substrate at 10...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Lysine-specific histone demethylase 1A
(Homo sapiens (Human))
University Of Utah
Curated by
ChEMBL
Ligand
BDBM151611
(SP-2509 | US11433053, Example HCI-2509 | US8987335...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 11nM
pH: 7.5 T: 2°C
Assay Description:
The LSD1 screening biochemical assay was performed by Shanghai ChemPartner Co. Ltd and the detailed protocol was shown as followed. The AlphaLISA ass...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
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MCE
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In Depth
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Article
PubMed
Copy BDB DOI
Target
Lysine-specific histone demethylase 1A
(Homo sapiens (Human))
University Of Utah
Curated by
ChEMBL
Ligand
BDBM151611
(SP-2509 | US11433053, Example HCI-2509 | US8987335...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 13nM
Assay Description:
The primary assay for compound inhibitory activity was the LSD1 Inhibitor Screening Assay Kit (Cayman Chemical Company, Ann Arbor, Mich.; Cayman Chem...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
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MCE
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PC sid
Similars
In Depth
Details
US Patent
Copy BDB DOI
Target
Lysine-specific histone demethylase 1A
(Homo sapiens (Human))
University Of Utah
Curated by
ChEMBL
Ligand
BDBM50445346
(CHEMBL3104250)
Copy SMILES
Copy InChI
Affinity Data
IC50: 13nM
Assay Description:
Inhibition of LSD1 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
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CHEMBL
PC cid
PC sid
Similars
In Depth
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Article
PubMed
Copy BDB DOI
Target
Lysine-specific histone demethylase 1A
(Homo sapiens (Human))
University Of Utah
Curated by
ChEMBL
Ligand
BDBM151611
(SP-2509 | US11433053, Example HCI-2509 | US8987335...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 13nM
Assay Description:
The primary assay for compound inhibitory activity was the LSD1 Inhibitor Screening Assay Kit (Cayman Chemical Company, Ann Arbor, Mich.; Cayman Chem...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
MCE
PC cid
PC sid
Similars
In Depth
Details
US Patent
Copy BDB DOI
Target
Lysine-specific histone demethylase 1A
(Homo sapiens (Human))
University Of Utah
Curated by
ChEMBL
Ligand
BDBM50445346
(CHEMBL3104250)
Copy SMILES
Copy InChI
Affinity Data
IC50: 13nM
Assay Description:
Inhibition of LSD1 (unknown origin) using dimethyl K4 peptide as substrate assessed as resorufin level by spectrophotometric analysis
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
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CHEMBL
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PC sid
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In Depth
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Article
PubMed
Copy BDB DOI
Target
Lysine-specific histone demethylase 1A
(Homo sapiens (Human))
University Of Utah
Curated by
ChEMBL
Ligand
BDBM50445346
(CHEMBL3104250)
Copy SMILES
Copy InChI
Affinity Data
IC50: 24nM
Assay Description:
Inhibition of recombinant LSD1 (unknown origin) using H3K4me2 as substrate by fluorescence assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
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CHEMBL
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In Depth
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Article
PubMed
Copy BDB DOI
Target
Lysine-specific histone demethylase 1A
(Homo sapiens (Human))
University Of Utah
Curated by
ChEMBL
Ligand
BDBM151611
(SP-2509 | US11433053, Example HCI-2509 | US8987335...)
Copy SMILES
Copy InChI
Affinity Data
IC50: <50nM
Assay Description:
The purpose of this test is to test the in vitro inhibitory activities of the compounds against LSD1. The enzyme used in this experiment was human LS...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
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MCE
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In Depth
Details
US Patent
Copy BDB DOI
Target
Cytochrome P450 2C9
(Homo sapiens (Human))
University Of Utah
Curated by
ChEMBL
Ligand
BDBM50445346
(CHEMBL3104250)
Copy SMILES
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Affinity Data
IC50: 8.04E+3nM
Assay Description:
Inhibition of CYP2C9 (unknown origin)
More data for this Ligand-Target Pair
Target Info
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KEGG
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CHEMBL
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PubMed
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Target
Cytochrome P450 2C19
(Homo sapiens (Human))
University Of Utah
Curated by
ChEMBL
Ligand
BDBM50445346
(CHEMBL3104250)
Copy SMILES
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Affinity Data
IC50: 9.76E+3nM
Assay Description:
Inhibition of CYP2C19 (unknown origin)
More data for this Ligand-Target Pair
Target Info
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KEGG
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CHEMBL
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Target
Cytochrome P450 2D6
(Homo sapiens (Human))
University Of Utah
Curated by
ChEMBL
Ligand
BDBM50445346
(CHEMBL3104250)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of CYP2D6 (unknown origin)
More data for this Ligand-Target Pair
Target Info
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Target
Cytochrome P450 1A2
(Homo sapiens (Human))
University Of Utah
Curated by
ChEMBL
Ligand
BDBM50445346
(CHEMBL3104250)
Copy SMILES
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of CYP1A2 (unknown origin)
More data for this Ligand-Target Pair
Target Info
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KEGG
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Target
Amine oxidase [flavin-containing] A
(Homo sapiens (Human))
University Of Utah Research Foundation
US Patent
Ligand
BDBM151611
(SP-2509 | US11433053, Example HCI-2509 | US8987335...)
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Affinity Data
IC50: >3.00E+5nM
Assay Description:
Inhibition of monoamine oxidase activity was carried used using the MAO-Glo.TM. Assay Kit according to the manufacturer's suggested protocol. Bri...
More data for this Ligand-Target Pair
Target Info
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US Patent
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Target
Amine oxidase [flavin-containing] B
(Homo sapiens (Human))
University Of Utah Research Foundation
US Patent
Ligand
BDBM151611
(SP-2509 | US11433053, Example HCI-2509 | US8987335...)
Copy SMILES
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Affinity Data
IC50: >3.00E+5nM
Assay Description:
Inhibition of monoamine oxidase activity was carried used using the MAO-GIo Assay Kit according to the manufacturer's suggested protocol. Briefly...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
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MCE
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In Depth
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US Patent
Copy BDB DOI
Target
Amine oxidase [flavin-containing] B
(Homo sapiens (Human))
University Of Utah Research Foundation
US Patent
Ligand
BDBM151611
(SP-2509 | US11433053, Example HCI-2509 | US8987335...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >3.00E+5nM
Assay Description:
Inhibition of monoamine oxidase activity was carried used using the MAO-Glo.TM. Assay Kit according to the manufacturer's suggested protocol. Bri...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
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Ligand Info
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MCE
PC cid
PC sid
Similars
In Depth
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US Patent
Copy BDB DOI
Target
Amine oxidase [flavin-containing] A
(Homo sapiens (Human))
University Of Utah Research Foundation
US Patent
Ligand
BDBM151611
(SP-2509 | US11433053, Example HCI-2509 | US8987335...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >3.00E+5nM
Assay Description:
Inhibition of monoamine oxidase activity was carried used using the MAO-GIo Assay Kit according to the manufacturer's suggested protocol. Briefly...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
MCE
PC cid
PC sid
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In Depth
Details
US Patent
Copy BDB DOI