Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 38 hits in this display
BDBM22334(BW A4C | BW4C | BWA4C | BWA4C, 10 | CHEMBL314360 |...)
BDBM22334(BW A4C | BW4C | BWA4C | BWA4C, 10 | CHEMBL314360 |...)
BDBM22334(BW A4C | BW4C | BWA4C | BWA4C, 10 | CHEMBL314360 |...)
BDBM22334(BW A4C | BW4C | BWA4C | BWA4C, 10 | CHEMBL314360 |...)
BDBM22334(BW A4C | BW4C | BWA4C | BWA4C, 10 | CHEMBL314360 |...)
BDBM22334(BW A4C | BW4C | BWA4C | BWA4C, 10 | CHEMBL314360 |...)
BDBM22334(BW A4C | BW4C | BWA4C | BWA4C, 10 | CHEMBL314360 |...)
BDBM22334(BW A4C | BW4C | BWA4C | BWA4C, 10 | CHEMBL314360 |...)
IC50: 50nMAssay Description:Inhibition of 5-LO in human neutrophils using arachidonic acid as substrate preincubated for 15 mins measured after 10 mins by HPLC analysisMore data for this Ligand-Target Pair
BDBM22334(BW A4C | BW4C | BWA4C | BWA4C, 10 | CHEMBL314360 |...)
BDBM22334(BW A4C | BW4C | BWA4C | BWA4C, 10 | CHEMBL314360 |...)
BDBM22334(BW A4C | BW4C | BWA4C | BWA4C, 10 | CHEMBL314360 |...)
BDBM22334(BW A4C | BW4C | BWA4C | BWA4C, 10 | CHEMBL314360 |...)
BDBM22334(BW A4C | BW4C | BWA4C | BWA4C, 10 | CHEMBL314360 |...)
IC50: 60nMAssay Description:Inhibition of 5-Lipoxygenase in arachidonic acid-stimulated human neutrophils after 15 mins by HPLC analysis in presence of A23187More data for this Ligand-Target Pair
BDBM22334(BW A4C | BW4C | BWA4C | BWA4C, 10 | CHEMBL314360 |...)
BDBM22334(BW A4C | BW4C | BWA4C | BWA4C, 10 | CHEMBL314360 |...)
BDBM22334(BW A4C | BW4C | BWA4C | BWA4C, 10 | CHEMBL314360 |...)
BDBM22334(BW A4C | BW4C | BWA4C | BWA4C, 10 | CHEMBL314360 |...)
BDBM22334(BW A4C | BW4C | BWA4C | BWA4C, 10 | CHEMBL314360 |...)
IC50: 80nMAssay Description:Inhibition of 5-lipoxygenase-mediated 5(S)-H(p)ETE formation in fMLP-stimulated human PMNL incubated 10 mins prior to fMLP challengeMore data for this Ligand-Target Pair
BDBM22334(BW A4C | BW4C | BWA4C | BWA4C, 10 | CHEMBL314360 |...)
BDBM22334(BW A4C | BW4C | BWA4C | BWA4C, 10 | CHEMBL314360 |...)
IC50: 100nMAssay Description:Inhibition of 5-LO in human leucocytes by measuring FLAP-dependent 5-LOproduct LTB4 in presence of calcium ionophore A23187More data for this Ligand-Target Pair
BDBM22334(BW A4C | BW4C | BWA4C | BWA4C, 10 | CHEMBL314360 |...)
IC50: 110nMAssay Description:Inhibition of FLAP in A23187-stimulated human neutrophils assessed as 5-LO product formation preincubated for 15 mins measured after 10 minsMore data for this Ligand-Target Pair
BDBM22334(BW A4C | BW4C | BWA4C | BWA4C, 10 | CHEMBL314360 |...)
IC50: 110nMAssay Description:Inhibition of 5-LO in human polymorphonuclear leukocytes assessed as inhibition of LTB4 production after 10 mins by RP-HPLC assayMore data for this Ligand-Target Pair
BDBM22334(BW A4C | BW4C | BWA4C | BWA4C, 10 | CHEMBL314360 |...)
BDBM22334(BW A4C | BW4C | BWA4C | BWA4C, 10 | CHEMBL314360 |...)
BDBM22334(BW A4C | BW4C | BWA4C | BWA4C, 10 | CHEMBL314360 |...)
BDBM22334(BW A4C | BW4C | BWA4C | BWA4C, 10 | CHEMBL314360 |...)
BDBM22334(BW A4C | BW4C | BWA4C | BWA4C, 10 | CHEMBL314360 |...)
BDBM22334(BW A4C | BW4C | BWA4C | BWA4C, 10 | CHEMBL314360 |...)
IC50: 160nMAssay Description:Inhibition of 5-lipoxygenase in A23187-stimulated human neutrophils assessed as inhibition of enzyme product formation by RP-HPLC analysisMore data for this Ligand-Target Pair
BDBM22334(BW A4C | BW4C | BWA4C | BWA4C, 10 | CHEMBL314360 |...)
BDBM22334(BW A4C | BW4C | BWA4C | BWA4C, 10 | CHEMBL314360 |...)
IC50: 160nMAssay Description:Inhibition of human recombinant 5-lipoxygenase-mediated product formation from arachidonic acid after 5 to 10 mins by HPLC analysisMore data for this Ligand-Target Pair
BDBM22334(BW A4C | BW4C | BWA4C | BWA4C, 10 | CHEMBL314360 |...)
BDBM22334(BW A4C | BW4C | BWA4C | BWA4C, 10 | CHEMBL314360 |...)
BDBM22334(BW A4C | BW4C | BWA4C | BWA4C, 10 | CHEMBL314360 |...)
BDBM22334(BW A4C | BW4C | BWA4C | BWA4C, 10 | CHEMBL314360 |...)
BDBM22334(BW A4C | BW4C | BWA4C | BWA4C, 10 | CHEMBL314360 |...)
IC50: 360nMAssay Description:Inhibition of human recombinant 5-LO in cell-free system assessed as inhibition of LTB4 production after 10 mins by RP-HPLC assayMore data for this Ligand-Target Pair
BDBM22334(BW A4C | BW4C | BWA4C | BWA4C, 10 | CHEMBL314360 |...)
BDBM22334(BW A4C | BW4C | BWA4C | BWA4C, 10 | CHEMBL314360 |...)
Lipoxygenase(Solanum tuberosum (potato))The University Of Sydney
BDBM22334(BW A4C | BW4C | BWA4C | BWA4C, 10 | CHEMBL314360 |...)