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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
2
hits in this display
Target
11-beta-hydroxysteroid dehydrogenase type 2
(Homo sapiens (Human))
University Of Natural Resources And Applied Life Sciences
Curated by
ChEMBL
Ligand
BDBM50329189
((3beta,18beta,20beta)-3-(Acetylamino)-11-oxo-olean...)
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Affinity Data
IC50: 458nM
Assay Description:
Inhibition of human recombinant 11beta-HSD2 expressed in HEK293 cells assessed as conversion of [1,2,6,7-3H]-cortisol to cortisone by scintillation c...
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
Article
PubMed
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Target
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human))
University Of Natural Resources And Applied Life Sciences
Curated by
ChEMBL
Ligand
BDBM50329189
((3beta,18beta,20beta)-3-(Acetylamino)-11-oxo-olean...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 825nM
Assay Description:
Inhibition of human recombinant 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [1,2-3H]-cortisone to cortisol by scintillation count...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI