Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetPlatelet-activating factor acetylhydrolase(Homo sapiens (Human))
Astex Pharmaceuticals

Curated by ChEMBL

LigandBDBM50197656(CHEMBL3959796)Copy SMILESCopy InChI

Affinity DataIC50:  250nMAssay Description:Inhibition of recombinant human Lp-PLA2 pre-incubated for 30 mins before PED6 fluorogenic substrateMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetPlatelet-activating factor acetylhydrolase(Homo sapiens (Human))
Astex Pharmaceuticals

Curated by ChEMBL

LigandBDBM50197656(CHEMBL3959796)Copy SMILESCopy InChI

Affinity DataIC50:  660nMAssay Description:Inhibition of Lp-PLA2 in whole human plasma pre-incubated for 15 mins before 2-thio-PAF substrate additionMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI