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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
1
hit in this display
Target
Cytochrome P450 family 11 subfamily B member 2
(Cercopithecus sabaeus)
Boehringer Ingelheim International
US Patent
Ligand
BDBM191541
(US9181272, 311)
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Affinity Data
IC50: 22.8nM
pH: 7.4
Assay Description:
The aldosterone synthase inhibition assay employs cynomolgus adrenal gland mitochondria as the source of aldosterone synthase (CYP11B2). Mitochondr...
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Target Info
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Ligand Info
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US Patent
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