Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetMelanocortin receptor 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50138299((S)-4-(4-Acetyl-piperazin-1-yl)-2-(4-chloro-benzyl...)
Affinity DataIC50:  11nMAssay Description:Inhibitory activity against [125I]-NDP-alpha-MSH binding to the human melanocortin 4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50138299((S)-4-(4-Acetyl-piperazin-1-yl)-2-(4-chloro-benzyl...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory activity against human melanocortin 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Mus musculus)
Amgen

Curated by ChEMBL
LigandPNGBDBM50138299((S)-4-(4-Acetyl-piperazin-1-yl)-2-(4-chloro-benzyl...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory activity against mouse melanocortin 1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50138299((S)-4-(4-Acetyl-piperazin-1-yl)-2-(4-chloro-benzyl...)
Affinity DataEC50: >1.00E+4nMAssay Description:Intracellular level of cAMP in cells expressing the melanocortin 4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed