Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 6 hits in this display   

TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50314220((R)-4-acetamido-2-(4-bromophenylsulfonamido)-N-hyd...)
Affinity DataIC50:  110nMAssay Description:Inhibition of human recombinant ADAM17 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50314220((R)-4-acetamido-2-(4-bromophenylsulfonamido)-N-hyd...)
Affinity DataIC50:  190nMAssay Description:Inhibition of MMP9 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50314220((R)-4-acetamido-2-(4-bromophenylsulfonamido)-N-hyd...)
Affinity DataIC50:  190nMAssay Description:Inhibition of MMP2 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50314220((R)-4-acetamido-2-(4-bromophenylsulfonamido)-N-hyd...)
Affinity DataIC50:  300nMAssay Description:Inhibition of human recombinant MMP14 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50314220((R)-4-acetamido-2-(4-bromophenylsulfonamido)-N-hyd...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of MMP1 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 10(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50314220((R)-4-acetamido-2-(4-bromophenylsulfonamido)-N-hyd...)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of human recombinant ADAM10 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed