Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetAdenosine receptor A2a(Homo sapiens (Human))
Neurocrine Bioscience

LigandBDBM26247(N-[2-(3,5-dimethyl-1H-pyrazol-1-yl)-6-[6-(morpholi...)Copy SMILESCopy InChI

Affinity DataKi:  0.830nM ΔG°:  -51.3kJ/molepH: 7.4 T: 2°CAssay Description:The membranes prepared from HEK cells transfected with adenosine receptors were used in binding assays. Nonspecific binding was determined in the pre...More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetAdenosine receptor A1(Homo sapiens (Human))
Neurocrine Bioscience

LigandBDBM26247(N-[2-(3,5-dimethyl-1H-pyrazol-1-yl)-6-[6-(morpholi...)Copy SMILESCopy InChI

Affinity DataKi:  130nMAssay Description:The membranes prepared from HEK cells transfected with adenosine receptors were used in binding assays. Nonspecific binding was determined in the pre...More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI