Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 16 hits in this display   

TargetAdenosine receptor A1(Rattus norvegicus (rat))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50094569(6-chloro-3,20-dioxo-1beta,2beta-dihydro-3'H-cyclop...)
Affinity DataKi:  1.30nMAssay Description:Adenosine A1 receptor binding was measured in adenosine deaminase (ADA) pretreated rat cortical membranes using [3H]cyclohexyladenosine in the presen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50094569(6-chloro-3,20-dioxo-1beta,2beta-dihydro-3'H-cyclop...)
Affinity DataKi:  14nMAssay Description:Binding affinity for human androgen receptor in transiently-transfected COS-1 cells.More data for this Ligand-Target Pair
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50094569(6-chloro-3,20-dioxo-1beta,2beta-dihydro-3'H-cyclop...)
Affinity DataKi:  636nMAssay Description:Binding to Adenosine A2 receptor was measured in ADA-pretreated rat striatal membranes using [3H]-CGS- 21680More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
The Pennsylvania State University

Curated by ChEMBL
LigandPNGBDBM50154009(Acetic acid 17-acetyl-6-chloro-10,13-dimethyl-3-ox...)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of CHO-K1 cells expressing glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50154009(Acetic acid 17-acetyl-6-chloro-10,13-dimethyl-3-ox...)
Affinity DataIC50:  4.70nMAssay Description:Inhibition of AR-dimerization in CHO-K1 cells expressing human androgen receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50094569(6-chloro-3,20-dioxo-1beta,2beta-dihydro-3'H-cyclop...)
Affinity DataIC50:  5nMAssay Description:Displacement of [3H]DPCPX from adenosine A1 receptor of rat cortical membranes without GTPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50154009(Acetic acid 17-acetyl-6-chloro-10,13-dimethyl-3-ox...)
Affinity DataIC50:  22nMAssay Description:Inhibition of human androgen receptor expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50094569(6-chloro-3,20-dioxo-1beta,2beta-dihydro-3'H-cyclop...)
Affinity DataIC50:  23nMAssay Description:Antagonistic activity against human androgen receptor (hAR) in co-transfected CV-1 cells.More data for this Ligand-Target Pair
TargetAndrogen receptor(Rattus norvegicus (Rat))
School Of Pharmacy And Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50535836(CHEMBL4558169)
Affinity DataIC50:  59nMAssay Description:Antagonist activity at rat androgen receptor fused with DNA-binding domain of GAL4 expressed in AR-UAS-bla GripTite 293 cells assessed as inhibition ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50154009(Acetic acid 17-acetyl-6-chloro-10,13-dimethyl-3-ox...)
Affinity DataIC50:  61nMAssay Description:Inhibition of human lymph node carcinoma of prostate (LNCaP) cell proliferationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50094569(6-chloro-3,20-dioxo-1beta,2beta-dihydro-3'H-cyclop...)
Affinity DataIC50:  125nMAssay Description:Displacement of [3H]DPCPX from adenosine A1 receptor of rat cortical membranes with GTPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50094569(6-chloro-3,20-dioxo-1beta,2beta-dihydro-3'H-cyclop...)
Affinity DataIC50:  259nMAssay Description:Antagonist activity at human AR AF2 assessed as inhibition of fluorescent-labelled D11-FxxLF peptide Co-activator to receptor by TR-FRET assayMore data for this Ligand-Target Pair
TargetAndrogen receptor(Rattus norvegicus (Rat))
School Of Pharmacy And Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50094569(6-chloro-3,20-dioxo-1beta,2beta-dihydro-3'H-cyclop...)
Affinity DataIC50:  631nMAssay Description:Inhibitory concentration against recombinant rat androgen receptor expressed in Escherichia coli using [3H]methyltrienolone (R 1881)More data for this Ligand-Target Pair
TargetProgesterone receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50094569(6-chloro-3,20-dioxo-1beta,2beta-dihydro-3'H-cyclop...)
Affinity DataIC50: >1.00E+3nMAssay Description:Antagonistic activity against human progesterone receptor B (hPR-B) in co-transfected CV-1 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Rattus norvegicus (Rat))
School Of Pharmacy And Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50094569(6-chloro-3,20-dioxo-1beta,2beta-dihydro-3'H-cyclop...)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of [3H]-R-1881 binding to rat ventral prostrate cytosolic androgen receptorMore data for this Ligand-Target Pair
TargetProtein LANA1(Human herpesvirus 8)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM50094569(6-chloro-3,20-dioxo-1beta,2beta-dihydro-3'H-cyclop...)
Affinity DataEC50: >7.50E+4nMAssay Description:Primary Collaborators: Kenneth Kaye,Brigham & Womens,Boston MA,kkaye@rics.bwh.harvard.edu,617-525-4256 Chantal Beauchemin,Brigham & Womens,Boston MA,...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay