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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
5
hits in this display
Target
D(3) dopamine receptor
(Homo sapiens (Human))
Aptuit
Curated by
ChEMBL
Ligand
BDBM50192318
(CHEMBL3979523 | US10239870, Example 284)
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Affinity Data
Ki: 0.209nM
Assay Description:
Displacement of [3H]-spiperone from human dopamine D3 receptor expressed in CHO-K1 cell membranes after 90 mins by liquid scintillation counting
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
D(3) dopamine receptor
(Rattus norvegicus (Rat))
Indivior
US Patent
Ligand
BDBM50192318
(CHEMBL3979523 | US10239870, Example 284)
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Affinity Data
Ki: 0.245nM
Assay Description:
[125I]-7OH-PIPAT Binding Assay at rat native D3 receptor on membranes from rat ventral striatum. Homogenates from frozen rat brain ventral striatum (...
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
US Patent
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Target
D(2) dopamine receptor
(Homo sapiens (Human))
Indivior
US Patent
Ligand
BDBM50192318
(CHEMBL3979523 | US10239870, Example 284)
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Affinity Data
Ki: 347nM
Assay Description:
CHO cells stably expressing human dopamine receptor type 2, long variant (hD2L), coupled to Gα16 protein (CHO-Gα16-hD2L) were re-suspended ...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
US Patent
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Aptuit
Curated by
ChEMBL
Ligand
BDBM50192318
(CHEMBL3979523 | US10239870, Example 284)
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Affinity Data
Ki: 447nM
Assay Description:
Displacement of [3H]-spiperone from human dopamine D2 receptor expressed in CHO-K1 cell membranes coexpressing Galpha16 after 120 mins by liquid scin...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human))
Aptuit
Curated by
ChEMBL
Ligand
BDBM50192318
(CHEMBL3979523 | US10239870, Example 284)
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Affinity Data
IC50: >100nM
Assay Description:
Inhibition of human ERG transfected in HEK293 cells assessed as reduction in tail current by patch clamp assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI