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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
6
hits in this display
Target
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
(Homo sapiens (Human))
Novartis Institute For Biomedical Research
Curated by
ChEMBL
Ligand
BDBM50372473
(CHEMBL270638)
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Affinity Data
IC50: 35nM
Assay Description:
Inhibition of PI3K p110delta
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
RAC-alpha serine/threonine-protein kinase
(Homo sapiens (Human))
Novartis Institute For Biomedical Research
Curated by
ChEMBL
Ligand
BDBM50372473
(CHEMBL270638)
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Copy InChI
Affinity Data
IC50: 45nM
Assay Description:
Inhibition of phosphorylation of T308-PKB in human U87MG cells by ELISA
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
(Homo sapiens (Human))
Novartis Institute For Biomedical Research
Curated by
ChEMBL
Ligand
BDBM50372473
(CHEMBL270638)
Copy SMILES
Copy InChI
Affinity Data
IC50: 56nM
Assay Description:
Inhibition of PI3K p110alpha
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
(Homo sapiens (Human))
Novartis Institute For Biomedical Research
Curated by
ChEMBL
Ligand
BDBM50372473
(CHEMBL270638)
Copy SMILES
Copy InChI
Affinity Data
IC50: 117nM
Assay Description:
Inhibition of PI3K p110gamma
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
3-phosphoinositide-dependent protein kinase 1
(Homo sapiens (Human))
Novartis Institute For Biomedical Research
Curated by
ChEMBL
Ligand
BDBM50372473
(CHEMBL270638)
Copy SMILES
Copy InChI
Affinity Data
IC50: 245nM
Assay Description:
Inhibition of PDK1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
(Homo sapiens (Human))
Novartis Institute For Biomedical Research
Curated by
ChEMBL
Ligand
BDBM50372473
(CHEMBL270638)
Copy SMILES
Copy InChI
Affinity Data
IC50: 446nM
Assay Description:
Inhibition of PI3K p110beta
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI