Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetAcyl-CoA desaturase 1(Mus musculus)
Xenon Pharmaceuticals

Curated by ChEMBL

LigandBDBM50424815(CHEMBL2315118)Copy SMILESCopy InChI

Affinity DataIC50:  113nMAssay Description:Inhibition of SCD1 in ICR mouse liver microsome using [9,10 3H]- stearoyl-Coenzyme A substrate assessed as decreased production of tritiated water af...More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetStearoyl-CoA desaturase(Homo sapiens (Human))
Xenon Pharmaceuticals

Curated by ChEMBL

LigandBDBM50424815(CHEMBL2315118)Copy SMILESCopy InChI

Affinity DataIC50:  119nMAssay Description:Inhibition of SCD1 in human HepG2 cells using [14C]-stearate substrate assessed as decreased production of [14C]-oleic acid after 24 hrsMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI