Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetNeprilysin(Homo sapiens (Human))
University Of Paris

Curated by ChEMBL

LigandBDBM50041054(3-(4-Hydroxy-phenyl)-2-(2-mercaptomethyl-3-phenyl-...)Copy SMILESCopy InChI

Affinity DataIC50:  2.5nMAssay Description:In vivo inhibitory potency against neutral endopeptidase by displacement of [3H]-HACBOGly binding in mouse kidneyMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetAngiotensin-converting enzyme(Mus musculus)
University Of Paris

Curated by ChEMBL

LigandBDBM50041054(3-(4-Hydroxy-phenyl)-2-(2-mercaptomethyl-3-phenyl-...)Copy SMILESCopy InChI

Affinity DataIC50:  4.30nMAssay Description:Inhibitory potency against angiotensin converting enzyme by displacement of [3H]-trandolaprilate binding in mouse lungMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI