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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
7
hits in this display
Target
Fatty-acid amide hydrolase 1
(Homo sapiens (Human))
Fondazione Istituto Italiano Di Tecnologia
US Patent
Ligand
BDBM50153372
(CHEMBL3774586 | US9630914, Example 8)
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Affinity Data
IC50: 22nM
Assay Description:
Human recombinant FAAH was obtained from a HEK-293 FAAH-1 overexpressing stable cell line. Cells were grown in DMEM medium containing 10% FBS, 1% pen...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
US Patent
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Target
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat))
Fondazione Istituto Italiano Di Tecnologia
Curated by
ChEMBL
Ligand
BDBM50153372
(CHEMBL3774586 | US9630914, Example 8)
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Affinity Data
IC50: 90nM
Assay Description:
Inhibition of FAAH in Sprague-Dawley rat brain homogenates preincubated for 10 mins followed by addition of substrate measured after 30 mins by liqui...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
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In Depth
Details
Article
PubMed
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Target
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat))
Fondazione Istituto Italiano Di Tecnologia
Curated by
ChEMBL
Ligand
BDBM50153372
(CHEMBL3774586 | US9630914, Example 8)
Copy SMILES
Copy InChI
Affinity Data
IC50: 90nM
Assay Description:
Rat FAAH was prepared from male Sprague Dawley rat brains, homogenized in a potter in 20 mM of Tris HCl pH 7.4, 0.32 M sucrose.The radiometric assay ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
US Patent
Copy BDB DOI
Target
Prostaglandin G/H synthase 1
(Ovis aries (Sheep))
Fondazione Istituto Italiano Di Tecnologia
Curated by
ChEMBL
Ligand
BDBM50153372
(CHEMBL3774586 | US9630914, Example 8)
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Affinity Data
IC50: 580nM
Assay Description:
Inhibition of ovine COX1 assessed as production of PGF2-alpha preincubated with compound followed by the addition of 5 uM arachidonic acid as substra...
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Prostaglandin G/H synthase 1
(Ovis aries (Sheep))
Fondazione Istituto Italiano Di Tecnologia
Curated by
ChEMBL
Ligand
BDBM50153372
(CHEMBL3774586 | US9630914, Example 8)
Copy SMILES
Copy InChI
Affinity Data
IC50: 580nM
Assay Description:
COX activity was measured using a commercial kit (COX Inhibitor Screening Assay Kit Cayman Chemical N. 560131) which includes both ovine COX-1 and hu...
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
US Patent
Copy BDB DOI
Target
Prostaglandin G/H synthase 2
(Homo sapiens (Human))
Fondazione Istituto Italiano Di Tecnologia
US Patent
Ligand
BDBM50153372
(CHEMBL3774586 | US9630914, Example 8)
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Copy InChI
Affinity Data
IC50: 6.20E+3nM
Assay Description:
COX activity was measured using a commercial kit (COX Inhibitor Screening Assay Kit Cayman Chemical N. 560131) which includes both ovine COX-1 and hu...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
US Patent
Copy BDB DOI
Target
Prostaglandin G/H synthase 2
(Homo sapiens (Human))
Fondazione Istituto Italiano Di Tecnologia
US Patent
Ligand
BDBM50153372
(CHEMBL3774586 | US9630914, Example 8)
Copy SMILES
Copy InChI
Affinity Data
IC50: 6.20E+3nM
Assay Description:
Inhibition of recombinant human COX2 assessed as production of PGF2-alpha preincubated with compound followed by the addition of 5 uM arachidonic aci...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI