Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Pfizer

Curated by ChEMBL

LigandBDBM50220575(4-(4-fluoro-phenyl)-1-[2-hydroxy-2-(6-hydroxy-biph...)Copy SMILESCopy InChI

Affinity DataIC50:  570nMAssay Description:Displacement of [3H]racemic CP101606 from rat NR2B receptor in P2 membraneMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetCytochrome P450 2D6(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM50220575(4-(4-fluoro-phenyl)-1-[2-hydroxy-2-(6-hydroxy-biph...)Copy SMILESCopy InChI

Affinity DataIC50:  8.40E+3nMAssay Description:Displacement of [3H]bufuralol from CYP2D6More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI