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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
3
hits in this display
Target
Beta-3 adrenergic receptor
(Canis familiaris)
Astellas Pharma
Curated by
ChEMBL
Ligand
BDBM50264709
((R)-5-(3-(2-(2-(3-chlorophenyl)-2-hydroxyethylamin...)
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Affinity Data
EC50: 1.60nM
Assay Description:
Agonist activity at dog cloned adrenergic beta3 receptor expressed in CHO cells assessed as cAMP accumulation
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Beta-1 adrenergic receptor
(Homo sapiens (Human))
Astellas Pharma
Curated by
ChEMBL
Ligand
BDBM50264709
((R)-5-(3-(2-(2-(3-chlorophenyl)-2-hydroxyethylamin...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 620nM
Assay Description:
Agonist activity at human cloned adrenergic beta1 receptor expressed in CHO cells assessed as cAMP accumulation
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Beta-3 adrenergic receptor
(Homo sapiens (Human))
Astellas Pharma
Curated by
ChEMBL
Ligand
BDBM50264709
((R)-5-(3-(2-(2-(3-chlorophenyl)-2-hydroxyethylamin...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 4.60nM
Assay Description:
Agonist activity at human cloned adrenergic beta3 receptor expressed in CHO cells assessed as cAMP accumulation
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI