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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
8
hits in this display
Target
Neuromedin-K receptor
(GUINEA PIG)
Cambridge University Forvie Site
Curated by
ChEMBL
Ligand
BDBM50050642
(CHEMBL296014 | {(S)-1-[(R)-1-(8-Hydroxy-octylcarba...)
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Affinity Data
IC50: 22nM
Assay Description:
Inhibitory activity against Tachykinin receptor 3 in guinea pig cortical membranes labeled with [125 I][MePhe7]-NKB
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Neuromedin-K receptor
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM50050642
(CHEMBL296014 | {(S)-1-[(R)-1-(8-Hydroxy-octylcarba...)
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Affinity Data
IC50: 40nM
Assay Description:
Compound was tested for binding affinity against human Tachykinin receptor 3 in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
Copy BDB DOI
Target
Neuromedin-K receptor
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM50050642
(CHEMBL296014 | {(S)-1-[(R)-1-(8-Hydroxy-octylcarba...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 40nM
Assay Description:
Inhibitory activity against cloned human Tachykinin receptor 3 in CHO cells labeled with [125I][MePhe7]-NKB
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neuromedin-K receptor
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM50050682
(CHEMBL298272 | {(S)-1-[1-(8-Hydroxy-octylcarbamoyl...)
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Affinity Data
IC50: 92nM
Assay Description:
Compound was tested for the inhibition of [125I]-[MePhe7]-NKB binding to cloned human Tachykinin receptor 3 in CHO cell lines
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neuromedin-K receptor
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM50050684
(CHEMBL430576 | {(S)-1-[(S)-1-(8-Hydroxy-octylcarba...)
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Affinity Data
IC50: 1.69E+3nM
Assay Description:
Compound was tested for the inhibition of [125I]-[MePhe7]-NKB binding to cloned human Tachykinin receptor 3 in CHO cell lines
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neuromedin-K receptor
(Rattus norvegicus)
Cambridge University Forvie Site
Curated by
ChEMBL
Ligand
BDBM50050642
(CHEMBL296014 | {(S)-1-[(R)-1-(8-Hydroxy-octylcarba...)
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Affinity Data
IC50: 2.79E+3nM
Assay Description:
In vitro inhibitory activity against senktide-evoked increases in intracellular calcium levels in cloned human Tachykinin receptor 3 in CHO cell line...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
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In Depth
Details
Article
PubMed
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Target
Substance-K receptor
(HAMSTER)
Cambridge University Forvie Site
Curated by
ChEMBL
Ligand
BDBM50050642
(CHEMBL296014 | {(S)-1-[(R)-1-(8-Hydroxy-octylcarba...)
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Affinity Data
IC50: 6.16E+3nM
Assay Description:
Inhibitory activity against Tachykinin receptor 2 in membranes prepared from hamster urinary bladder labeled with [125 I] NKA
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
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In Depth
Details
Article
PubMed
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Target
Substance-P receptor
(Homo sapiens (Human))
Cambridge University Forvie Site
Curated by
ChEMBL
Ligand
BDBM50050642
(CHEMBL296014 | {(S)-1-[(R)-1-(8-Hydroxy-octylcarba...)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibitory activity against Tachykinin receptor 1 in human lymphoma IM9 cells labeled with [125 I] Bolton-Hunter substance P
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI