Home
About
Info
Download
WebServices
Contact
Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
3
hits in this display
Target
Mast/stem cell growth factor receptor Kit [D816V]
(Homo sapiens (Human))
Blueprint Medicines
US Patent
Ligand
BDBM175771
(US9688680, 316)
Copy SMILES
Copy InChI
Affinity Data
IC50: 5.5nM
pH: 7.5 T: 2°C
Assay Description:
In each well of a 384-well plate, 0.2 ng/ul final (2 nM) of wild type Kit (Carna Bioscience 08-156) was incubated in a total of 12.5 ul of buffer (10...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Mast/stem cell growth factor receptor Kit [V560G,D816V]
(Homo sapiens (Human))
Blueprint Medicines
US Patent
Ligand
BDBM175771
(US9688680, 316)
Copy SMILES
Copy InChI
Affinity Data
IC50: 55nM
T: 2°C
Assay Description:
10,000 HMC1.2 cells were incubated in 22 ul culture media (phenol-red free IMDM, no serum) in each well of a 384-well plate and serum starved overnig...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human))
Blueprint Medicines
US Patent
Ligand
BDBM175771
(US9688680, 316)
Copy SMILES
Copy InChI
Affinity Data
IC50: 550nM
pH: 7.5 T: 2°C
Assay Description:
In each well of a 384-well plate, 0.04 ng/ul (0.5 nM) of D816V Kit (Carna Bioscience 08-156) was incubated in a total of 12.5 ul of buffer (100 mM HE...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI