Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 12 hits in this display
BDBM50448963(CHEMBL3125537 | US9296736, 351 | US9593129, Exampl...)
BDBM50448963(CHEMBL3125537 | US9296736, 351 | US9593129, Exampl...)
BDBM50448963(CHEMBL3125537 | US9296736, 351 | US9593129, Exampl...)
BDBM50448963(CHEMBL3125537 | US9296736, 351 | US9593129, Exampl...)
BDBM50448963(CHEMBL3125537 | US9296736, 351 | US9593129, Exampl...)
IC50: 0.100nMAssay Description:Binding affinity to human GST-thrombin-tagged MDM2 assessed as inhibition of interaction with human p53 after 1 hr by HTRF assayMore data for this Ligand-Target Pair
BDBM50448963(CHEMBL3125537 | US9296736, 351 | US9593129, Exampl...)
BDBM50448963(CHEMBL3125537 | US9296736, 351 | US9593129, Exampl...)
BDBM50448963(CHEMBL3125537 | US9296736, 351 | US9593129, Exampl...)
BDBM50448963(CHEMBL3125537 | US9296736, 351 | US9593129, Exampl...)
BDBM50448963(CHEMBL3125537 | US9296736, 351 | US9593129, Exampl...)
BDBM50448963(CHEMBL3125537 | US9296736, 351 | US9593129, Exampl...)
IC50: 18nMAssay Description:Binding affinity to MDM2 in human SJSA1 cells assessed as induction of p21 gene level after 7 hrs by qRT-PCR assay in presence of 10% human serumMore data for this Ligand-Target Pair
BDBM50448963(CHEMBL3125537 | US9296736, 351 | US9593129, Exampl...)