Home
About
Info
Download
WebServices
Contact
Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
12
hits in this display
Target
Arachidonate 5-lipoxygenase-activating protein
(Homo sapiens (Human))
Amira Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50052018
(3-[3-tert-Butylsulfanyl-1-(4-chloro-benzyl)-5-(qui...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 0.5nM
Assay Description:
Inhibition of FLAP in human peripheral leukocytes assessed as inhibition of calcium ionophore A23187-induced LTB4 production after 10 mins by ELISA
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Arachidonate 5-lipoxygenase-activating protein
(Homo sapiens (Human))
Amira Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50052018
(3-[3-tert-Butylsulfanyl-1-(4-chloro-benzyl)-5-(qui...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1nM
Assay Description:
Inhibition of FLAP in human peripheral leukocytes assessed as inhibition of calcium ionophore A23187-induced LTB4 production after 5 mins by ELISA in...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Arachidonate 5-lipoxygenase-activating protein
(Homo sapiens (Human))
Amira Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50052018
(3-[3-tert-Butylsulfanyl-1-(4-chloro-benzyl)-5-(qui...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1nM
Assay Description:
Inhibition of FLAP in human peripheral leukocytes assessed as inhibition of calcium ionophore A23187-induced LTB4 production after 1 hr by ELISA in a...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Arachidonate 5-lipoxygenase-activating protein
(Homo sapiens (Human))
Amira Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50052018
(3-[3-tert-Butylsulfanyl-1-(4-chloro-benzyl)-5-(qui...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.90nM
Assay Description:
Displacement of [3H]-3-[5-(pyrid-2-ylmethoxy)-3-tert-butylthio-1-benzylindol-2-yl]-2,2-dimethylpropionic acid from FLAP in human polymorphonuclear ce...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50052018
(3-[3-tert-Butylsulfanyl-1-(4-chloro-benzyl)-5-(qui...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 8nM
Assay Description:
Inhibition of calcium ionophore (A-23187)-stimulated LTB4 formation in human neutrophil assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Arachidonate 5-lipoxygenase-activating protein
(Rattus norvegicus)
Amira Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50052018
(3-[3-tert-Butylsulfanyl-1-(4-chloro-benzyl)-5-(qui...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 10nM
Assay Description:
Inhibition of FLAP in rat whole blood assessed as inhibition of calcium ionophore A23187-induced LTB4 production preincubated for 4 hrs by ELISA
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Arachidonate 5-lipoxygenase-activating protein
(Homo sapiens (Human))
Amira Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50052018
(3-[3-tert-Butylsulfanyl-1-(4-chloro-benzyl)-5-(qui...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 12nM
Assay Description:
Inhibition of FLAP in human peripheral leukocytes assessed as inhibition of calcium ionophore A23187-induced LTB4 production after 3 hr by ELISA in p...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Arachidonate 5-lipoxygenase-activating protein
(Homo sapiens (Human))
Amira Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50052018
(3-[3-tert-Butylsulfanyl-1-(4-chloro-benzyl)-5-(qui...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 66nM
Assay Description:
Inhibition of FLAP in human peripheral leukocytes assessed as inhibition of calcium ionophore A23187-induced LTB4 production after 10 mins by ELISA i...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Arachidonate 5-lipoxygenase-activating protein
(Homo sapiens (Human))
Amira Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50052018
(3-[3-tert-Butylsulfanyl-1-(4-chloro-benzyl)-5-(qui...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 80nM
Assay Description:
Inhibition of FLAP in human whole blood assessed as inhibition of calcium ionophore A23187-induced LTB4 production preincubated for 11 hrs by ELISA
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Arachidonate 5-lipoxygenase-activating protein
(Homo sapiens (Human))
Amira Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50052018
(3-[3-tert-Butylsulfanyl-1-(4-chloro-benzyl)-5-(qui...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 108nM
Assay Description:
Inhibition of FLAP in human whole blood assessed as inhibition of calcium ionophore A23187-induced LTB4 production preincubated for 5 hrs by ELISA
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Arachidonate 5-lipoxygenase-activating protein
(Rattus norvegicus)
Amira Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50052018
(3-[3-tert-Butylsulfanyl-1-(4-chloro-benzyl)-5-(qui...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 117nM
Assay Description:
Inhibition of FLAP in rat whole blood assessed as inhibition of calcium ionophore A23187-induced LTB4 production preincubated for 15 mins by ELISA
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Arachidonate 5-lipoxygenase-activating protein
(Homo sapiens (Human))
Amira Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50052018
(3-[3-tert-Butylsulfanyl-1-(4-chloro-benzyl)-5-(qui...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 536nM
Assay Description:
Inhibition of FLAP in human whole blood assessed as inhibition of calcium ionophore A23187-induced LTB4 production preincubated for 15 mins by ELISA
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI