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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
Mitogen-activated protein kinase 14
(Homo sapiens (Human))
Chemical Genomics Centre Of The Max Planck Society
Curated by
ChEMBL
Ligand
BDBM50303585
(1-(3-tert-butyl-1-(3-nitrophenyl)-1H-pyrazol-5-yl)...)
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Affinity Data
IC50: 120nM
Assay Description:
Inhibition of p38alpha active form expressed in Escherichia coli BL21(DE3) cells by HTRF assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
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In Depth
Details
Article
PubMed
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Target
Mitogen-activated protein kinase 14
(Homo sapiens (Human))
Chemical Genomics Centre Of The Max Planck Society
Curated by
ChEMBL
Ligand
BDBM50303585
(1-(3-tert-butyl-1-(3-nitrophenyl)-1H-pyrazol-5-yl)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 220nM
Assay Description:
Displacemnt of N,N'-(2,2'-(3,3'-disulfanediylbis(2,5-dioxopyrrolidine-3,1-diyl))bis(ethane-2,1-diyl))bis(2-(3-(3-tert-butyl-5-(3-naphthalen-1-ylureid...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Discoidin domain-containing receptor 2
(Homo sapiens (Human))
Technical University Of Dortmund
Curated by
ChEMBL
Ligand
BDBM50303585
(1-(3-tert-butyl-1-(3-nitrophenyl)-1H-pyrazol-5-yl)...)
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Affinity Data
IC50: 856nM
Assay Description:
Inhibition of wild type DDR2 (unknown origin) preincubated for 30 mins before substrate addition by FRET assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Discoidin domain-containing receptor 2
(Homo sapiens (Human))
Technical University Of Dortmund
Curated by
ChEMBL
Ligand
BDBM50303585
(1-(3-tert-butyl-1-(3-nitrophenyl)-1H-pyrazol-5-yl)...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 412nM
Assay Description:
Binding affinity to human acrylodan-labeled N-terminal His-tagged DDR2 (558 to 855 aa) by FLiK assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI