Home
About
Info
Download
WebServices
Contact
Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
8
hits in this display
Target
Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50300691
(Benzo[d]imidazo[2,1-b]thiazole-2-carboxylic acid {...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 1.60nM
Assay Description:
Binding affinity to FLT3 catalytic domain expressed in HEK293 cells by competitive binding assay
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50300691
(Benzo[d]imidazo[2,1-b]thiazole-2-carboxylic acid {...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >200nM
Assay Description:
Binding affinity to VEGFR2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50300691
(Benzo[d]imidazo[2,1-b]thiazole-2-carboxylic acid {...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 1.60nM
Assay Description:
Binding affinity to FLT3
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Platelet-derived growth factor receptor beta
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50300691
(Benzo[d]imidazo[2,1-b]thiazole-2-carboxylic acid {...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 2.20nM
Assay Description:
Binding affinity to PDGFRbeta
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Macrophage colony-stimulating factor 1 receptor
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50300691
(Benzo[d]imidazo[2,1-b]thiazole-2-carboxylic acid {...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 10nM
Assay Description:
Binding affinity to CSF1R
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Proto-oncogene tyrosine-protein kinase receptor Ret
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50300691
(Benzo[d]imidazo[2,1-b]thiazole-2-carboxylic acid {...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 3nM
Assay Description:
Binding affinity to RET
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Platelet-derived growth factor receptor alpha
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50300691
(Benzo[d]imidazo[2,1-b]thiazole-2-carboxylic acid {...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 4.30nM
Assay Description:
Binding affinity to PDGFRalpha
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM50300691
(Benzo[d]imidazo[2,1-b]thiazole-2-carboxylic acid {...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 7.5nM
Assay Description:
Binding affinity to KIT
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI