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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
5
hits in this display
Target
Mitogen-activated protein kinase 11/12/13/14
(Homo sapiens (Human))
Bayer Research Center
Curated by
ChEMBL
Ligand
BDBM50105619
(1-(5-tert-Butyl-isoxazol-3-yl)-3-(4-phenoxy-phenyl...)
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Affinity Data
IC50: 360nM
Assay Description:
Inhibition of Escherichia coli derived Mitogen-activated protein kinase p38
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
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Target
RAF proto-oncogene serine/threonine-protein kinase
(Homo sapiens (Human))
Bayer Research Center
Curated by
ChEMBL
Ligand
BDBM50105619
(1-(5-tert-Butyl-isoxazol-3-yl)-3-(4-phenoxy-phenyl...)
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Copy InChI
Affinity Data
IC50: 540nM
Assay Description:
Inhibitory concentration against raf kinase.
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
RAF proto-oncogene serine/threonine-protein kinase
(Homo sapiens (Human))
Bayer Research Center
Curated by
ChEMBL
Ligand
BDBM50105619
(1-(5-tert-Butyl-isoxazol-3-yl)-3-(4-phenoxy-phenyl...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.10E+3nM
Assay Description:
Inhibition of B-Raf1 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
RAF proto-oncogene serine/threonine-protein kinase
(Homo sapiens (Human))
Bayer Research Center
Curated by
ChEMBL
Ligand
BDBM50105619
(1-(5-tert-Butyl-isoxazol-3-yl)-3-(4-phenoxy-phenyl...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.10E+3nM
Assay Description:
Inhibition of RAF1 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
PubMed
Copy BDB DOI
Target
RAF proto-oncogene serine/threonine-protein kinase
(Homo sapiens (Human))
Bayer Research Center
Curated by
ChEMBL
Ligand
BDBM50105619
(1-(5-tert-Butyl-isoxazol-3-yl)-3-(4-phenoxy-phenyl...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.10E+3nM
Assay Description:
Inhibitory activity against human Raf-1 kinase
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI