Home
About
Info
Download
WebServices
Contact
Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
9
hits in this display
Target
Prostaglandin G/H synthase 2
(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50063783
(1-(3,5-Di-tert-butyl-4-hydroxy-phenyl)-hex-5-yn-1-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 100nM
Assay Description:
Inhibitory activity against prostaglandin G/H synthase 2 (COX-2)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Prostaglandin G/H synthase 2
(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50063783
(1-(3,5-Di-tert-butyl-4-hydroxy-phenyl)-hex-5-yn-1-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 100nM
Assay Description:
Concentration (in microM) to inhibit 50% of Prostaglandin G/H synthase 2 (COX-2) and is expressed in IC50.
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Prostaglandin G/H synthase 2
(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50063783
(1-(3,5-Di-tert-butyl-4-hydroxy-phenyl)-hex-5-yn-1-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 100nM
Assay Description:
Inhibition of Prostaglandin G/H synthase 2 (COX-2).
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Prostaglandin G/H synthase 1
(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50063783
(1-(3,5-Di-tert-butyl-4-hydroxy-phenyl)-hex-5-yn-1-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 250nM
Assay Description:
Inhibition of Prostaglandin G/H synthase 1 (COX-1).
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Prostaglandin G/H synthase 1
(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50063783
(1-(3,5-Di-tert-butyl-4-hydroxy-phenyl)-hex-5-yn-1-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 250nM
Assay Description:
Concentration (in microM) to inhibit 50% of Prostaglandin G/H synthase 1 (COX-1) and is expressed in IC50.
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Prostaglandin G/H synthase 1
(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50063783
(1-(3,5-Di-tert-butyl-4-hydroxy-phenyl)-hex-5-yn-1-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 250nM
Assay Description:
Inhibitory activity against prostaglandin G/H synthase 1 (COX-1)
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50063783
(1-(3,5-Di-tert-butyl-4-hydroxy-phenyl)-hex-5-yn-1-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3.00E+3nM
Assay Description:
Inhibition of 5-Lipoxygenase(5-LOX)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50063783
(1-(3,5-Di-tert-butyl-4-hydroxy-phenyl)-hex-5-yn-1-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3.00E+3nM
Assay Description:
The compound was tested for the concentration (in microM) to inhibit 50% of 5-Lipoxygenase (5-LOX) and is expressed in IC50.
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Polyunsaturated fatty acid 5-lipoxygenase
(Rattus norvegicus)
Procter & Gamble Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50063783
(1-(3,5-Di-tert-butyl-4-hydroxy-phenyl)-hex-5-yn-1-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3.00E+3nM
Assay Description:
Inhibition of 1-lipoxygenase (LOX)in RBL cells
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI