Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL

LigandBDBM50066571(7-tert-Butyl-3,3-dimethyl-5-thiophen-2-yl-2,3-dihy...)Copy SMILESCopy InChI

Affinity DataIC50:  70nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatents

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL

LigandBDBM50066571(7-tert-Butyl-3,3-dimethyl-5-thiophen-2-yl-2,3-dihy...)Copy SMILESCopy InChI

Affinity DataIC50:  200nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 1 (COX-1)More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatents

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL

LigandBDBM50066571(7-tert-Butyl-3,3-dimethyl-5-thiophen-2-yl-2,3-dihy...)Copy SMILESCopy InChI

Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition of 5-Lipoxygenase(5-LOX)More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatents

In DepthDetails ArticlePubMed
Copy BDB DOI