Home
About
Info
Download
WebServices
Contact
Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
12
hits in this display
Target
Delta-type opioid receptor
(Homo sapiens (Human))
The University Of Arizona
Curated by
ChEMBL
Ligand
BDBM50068132
(3-[(4-Benzyl-piperazin-1-yl)-(4-tert-butyl-phenyl)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 5.5nM
Assay Description:
Binding affinity was measured against cloned human Opioid receptor delta 1 (wild-type,Wt)
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Delta-type opioid receptor
(Rattus norvegicus (rat))
The University Of Arizona
Curated by
ChEMBL
Ligand
BDBM50068132
(3-[(4-Benzyl-piperazin-1-yl)-(4-tert-butyl-phenyl)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 8.40nM
Assay Description:
Binding affinity was measured against Opioid receptor delta 1 using [3H]-p-Cl-DPDPE as radioligand.
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Delta-type opioid receptor
(Rattus norvegicus (rat))
The University Of Arizona
Curated by
ChEMBL
Ligand
BDBM50068132
(3-[(4-Benzyl-piperazin-1-yl)-(4-tert-butyl-phenyl)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 8.40nM
Assay Description:
In vitro inhibition of [3H]-deltorphin binding to Opioid receptor delta 1 using rat brain membranes.
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Delta-type opioid receptor
(Rattus norvegicus (rat))
The University Of Arizona
Curated by
ChEMBL
Ligand
BDBM50068132
(3-[(4-Benzyl-piperazin-1-yl)-(4-tert-butyl-phenyl)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 8.40nM
Assay Description:
Binding affinity was measured against Opioid receptor delta 1 using [3H]-p-Cl-DPDPE as radioligand.
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Delta-type opioid receptor
(Homo sapiens (Human))
The University Of Arizona
Curated by
ChEMBL
Ligand
BDBM50068132
(3-[(4-Benzyl-piperazin-1-yl)-(4-tert-butyl-phenyl)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 17nM
Assay Description:
Binding affinity was measured against mutated human Opioid receptor delta 1 (W248L)
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mu-type opioid receptor
(Rattus norvegicus (rat))
The University Of Arizona
Curated by
ChEMBL
Ligand
BDBM50068132
(3-[(4-Benzyl-piperazin-1-yl)-(4-tert-butyl-phenyl)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.10E+4nM
Assay Description:
Binding affinity was measured against Opioid receptor mu 1 using [3H]-DAMGO as radioligand.
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mu-type opioid receptor
(Rattus norvegicus (rat))
The University Of Arizona
Curated by
ChEMBL
Ligand
BDBM50068132
(3-[(4-Benzyl-piperazin-1-yl)-(4-tert-butyl-phenyl)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.10E+4nM
Assay Description:
Binding affinity was measured against Opioid receptor mu 1 using [3H]-DAMGO as radioligand.
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mu-type opioid receptor
(Rattus norvegicus (rat))
The University Of Arizona
Curated by
ChEMBL
Ligand
BDBM50068132
(3-[(4-Benzyl-piperazin-1-yl)-(4-tert-butyl-phenyl)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.70E+4nM
Assay Description:
In vitro inhibition of [3H]-DAMGO (Tyr-D-Ala-Gly-(Me)-Phe-Gly-ol) binding to Opioid receptor mu 1 using rat brain membranes
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Delta-type opioid receptor
(MOUSE)
The University Of Arizona
Curated by
ChEMBL
Ligand
BDBM50068132
(3-[(4-Benzyl-piperazin-1-yl)-(4-tert-butyl-phenyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 210nM
Assay Description:
Tested for electrically induced smooth muscle contractions from mouse vas deferens expressed in delta opioid receptors
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mu-type opioid receptor
(GUINEA PIG)
The University Of Arizona
Curated by
ChEMBL
Ligand
BDBM50068132
(3-[(4-Benzyl-piperazin-1-yl)-(4-tert-butyl-phenyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 3.90E+4nM
Assay Description:
Tested for electrically induced smooth muscle contractions from guinea pig ileum expressed in mu opioid receptors
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mu-type opioid receptor
(GUINEA PIG)
The University Of Arizona
Curated by
ChEMBL
Ligand
BDBM50068132
(3-[(4-Benzyl-piperazin-1-yl)-(4-tert-butyl-phenyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 7.60E+3nM
Assay Description:
Tested for electrically induced smooth muscle contractions from guinea pig ileum expressed in mu opioid receptors
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Delta-type opioid receptor
(MOUSE)
The University Of Arizona
Curated by
ChEMBL
Ligand
BDBM50068132
(3-[(4-Benzyl-piperazin-1-yl)-(4-tert-butyl-phenyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 210nM
Assay Description:
Tested for electrically induced smooth muscle contractions from mouse vas deferens expressed in delta opioid receptors
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI