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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
2
hits in this display
Target
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research
Curated by
ChEMBL
Ligand
BDBM50045659
(3-[1-(4-Chloro-benzyl)-6-(5-phenyl-pyridin-2-ylmet...)
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Affinity Data
IC50: 100nM
Assay Description:
In vitro inhibition of LTB4 biosynthesis in [Ca2+]-ionophore-activated human polymorphonuclear leukocytes
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Polyunsaturated fatty acid 5-lipoxygenase
(Rattus norvegicus)
Merck Frosst Centre For Therapeutic Research
Curated by
ChEMBL
Ligand
BDBM50045659
(3-[1-(4-Chloro-benzyl)-6-(5-phenyl-pyridin-2-ylmet...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 200nM
Assay Description:
In vitro test for inhibition of 5-lipoxygenase in cell-free preparations from rat PMN leukocytes
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI