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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
5
hits in this display
Target
Adenosine receptor A2b
(Homo sapiens (Human))
Ligand Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50331920
(2-(4-(4-fluorophenethyl)-2-oxo-3-(thiazol-2-yl)-1,...)
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Affinity Data
Ki: 10nM
Assay Description:
Antagonist activity at adenosien A2B receptor in human HMC-1 cells assessed as inhibition of NECA-induced IL-8 release after 6 hr by ELISA
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Adenosine receptor A2b
(Homo sapiens (Human))
Ligand Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50331920
(2-(4-(4-fluorophenethyl)-2-oxo-3-(thiazol-2-yl)-1,...)
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Copy InChI
Affinity Data
Ki: 41nM
Assay Description:
Antagonist activity at human adenosine A2B receptor transfected in CHO cells assessed as inhibition of NECA-induced cAMP accumulation treated 15 mins...
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Adenosine receptor A2b
(Homo sapiens (Human))
Ligand Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50331920
(2-(4-(4-fluorophenethyl)-2-oxo-3-(thiazol-2-yl)-1,...)
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Copy InChI
Affinity Data
Ki: 105nM
Assay Description:
Displacement of [3H]ZM241385 from human adenosine A2B receptor transfected in CHO cells after 60 mins by scintillation counting
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Adenosine receptor A1
(Homo sapiens (Human))
Ligand Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50331920
(2-(4-(4-fluorophenethyl)-2-oxo-3-(thiazol-2-yl)-1,...)
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Affinity Data
Ki: 1.15E+3nM
Assay Description:
Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO-K1 cells after 2 hrs
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Adenosine receptor A2a
(Homo sapiens (Human))
Ligand Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50331920
(2-(4-(4-fluorophenethyl)-2-oxo-3-(thiazol-2-yl)-1,...)
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Copy InChI
Affinity Data
Ki: >1.00E+4nM
Assay Description:
Displacement of [3H]SCH58261 from human adenosine A2A receptor transfected in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI