Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 5 hits in this display   

TargetAdenosine receptor A2b(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50331920(2-(4-(4-fluorophenethyl)-2-oxo-3-(thiazol-2-yl)-1,...)
Affinity DataKi:  10nMAssay Description:Antagonist activity at adenosien A2B receptor in human HMC-1 cells assessed as inhibition of NECA-induced IL-8 release after 6 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50331920(2-(4-(4-fluorophenethyl)-2-oxo-3-(thiazol-2-yl)-1,...)
Affinity DataKi:  41nMAssay Description:Antagonist activity at human adenosine A2B receptor transfected in CHO cells assessed as inhibition of NECA-induced cAMP accumulation treated 15 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50331920(2-(4-(4-fluorophenethyl)-2-oxo-3-(thiazol-2-yl)-1,...)
Affinity DataKi:  105nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2B receptor transfected in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50331920(2-(4-(4-fluorophenethyl)-2-oxo-3-(thiazol-2-yl)-1,...)
Affinity DataKi:  1.15E+3nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO-K1 cells after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50331920(2-(4-(4-fluorophenethyl)-2-oxo-3-(thiazol-2-yl)-1,...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]SCH58261 from human adenosine A2A receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed