Home
About
Info
Download
WebServices
Contact
Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
9
hits in this display
Target
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by
ChEMBL
Ligand
BDBM50162973
(CHEMBL177298 | N-[4-(Benzothiazol-6-ylamino)-6-(1-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 40nM
Assay Description:
In vitro inhibition of Vascular endothelial growth factor receptor 2 at 10 uM ATP
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by
ChEMBL
Ligand
BDBM50162973
(CHEMBL177298 | N-[4-(Benzothiazol-6-ylamino)-6-(1-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 40nM
Assay Description:
In vitro inhibition of Vascular endothelial growth factor receptor 2 at 10 uM ATP
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Insulin receptor
(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by
ChEMBL
Ligand
BDBM50162973
(CHEMBL177298 | N-[4-(Benzothiazol-6-ylamino)-6-(1-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 420nM
Assay Description:
Inhibition of beta IRK tyrosine kinase
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Angiopoietin-1 receptor
(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by
ChEMBL
Ligand
BDBM50162973
(CHEMBL177298 | N-[4-(Benzothiazol-6-ylamino)-6-(1-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 700nM
Assay Description:
Inhibition of tyrosine protein kinase receptor TIE-2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Platelet-derived growth factor receptor alpha/beta
(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by
ChEMBL
Ligand
BDBM50162973
(CHEMBL177298 | N-[4-(Benzothiazol-6-ylamino)-6-(1-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3.90E+3nM
Assay Description:
Inhibition of PDGF-R2 tyrosine kinase
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Fibroblast growth factor receptor 1
(Mus musculus)
Johnson & Johnson Pharmaceutical Research And Development
Curated by
ChEMBL
Ligand
BDBM50162973
(CHEMBL177298 | N-[4-(Benzothiazol-6-ylamino)-6-(1-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of mouse Fibroblast growth factor receptor 1 expressed in NIH 3T3 fibroblasts
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by
ChEMBL
Ligand
BDBM50162973
(CHEMBL177298 | N-[4-(Benzothiazol-6-ylamino)-6-(1-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of human epidermal growth factor receptor
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Insulin receptor
(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by
ChEMBL
Ligand
BDBM50162973
(CHEMBL177298 | N-[4-(Benzothiazol-6-ylamino)-6-(1-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of human Insulin receptor expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Macrophage colony-stimulating factor 1 receptor
(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by
ChEMBL
Ligand
BDBM50162973
(CHEMBL177298 | N-[4-(Benzothiazol-6-ylamino)-6-(1-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.40E+4nM
Assay Description:
Inhibition of c-fms tyrosine kinase
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI