Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetAcetylcholinesterase(Homo sapiens (Human))TBA

LigandBDBM50343140(CHEMBL1770314 | Neocyclomorusin)Copy SMILESCopy InChI

Affinity DataKi:  3.10E+3nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidSimilars

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TargetCholinesterase(Homo sapiens (Human))TBA

LigandBDBM50343140(CHEMBL1770314 | Neocyclomorusin)Copy SMILESCopy InChI

Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of BuChE (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidSimilars

In DepthDetails Article
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TargetBeta-secretase 1(Homo sapiens (Human))
Gyeongsang National University

Curated by ChEMBL

LigandBDBM50343140(CHEMBL1770314 | Neocyclomorusin)Copy SMILESCopy InChI

Affinity DataIC50:  1.46E+5nMAssay Description:Inhibition of human recombinant BACE-1 expressed in HEK293 cells assessed as inhibition of amyloid precursor protein cleavage into amyloid beta after...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI