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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
5
hits in this display
Target
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50197402
(2-(4-chloro-phenoxy)-2-methyl-N-(5-sulfamoyl-adama...)
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Affinity Data
Ki: 5nM
Assay Description:
Inhibition of human HSD1 assessed as interconversion of cortisone to cortisol
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
11-beta-hydroxysteroid dehydrogenase 1
(Mus musculus (mouse))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50197402
(2-(4-chloro-phenoxy)-2-methyl-N-(5-sulfamoyl-adama...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 5nM
Assay Description:
Inhibition of mouse HSD1 assessed as interconversion of cortisone to cortisol
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50197402
(2-(4-chloro-phenoxy)-2-methyl-N-(5-sulfamoyl-adama...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 230nM
Assay Description:
Inhibition of human HSD1 expressed in HEK cells
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
11-beta-hydroxysteroid dehydrogenase type 2
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50197402
(2-(4-chloro-phenoxy)-2-methyl-N-(5-sulfamoyl-adama...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.60E+4nM
Assay Description:
Inhibition of human HSD2 assessed as interconversion of cortisone to cortisol
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
11-beta-hydroxysteroid dehydrogenase type 2
(Mus musculus (mouse))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50197402
(2-(4-chloro-phenoxy)-2-methyl-N-(5-sulfamoyl-adama...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+5nM
Assay Description:
Inhibition of mouse HSD2 assessed as interconversion of cortisone to cortisol
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI