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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
13
hits in this display
Target
Kinesin-like protein KIF11
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM50382559
(ISPINESIB)
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Affinity Data
Ki: 2.30nM
Assay Description:
Inhibition of Kinesin Eg5 (unknown origin)
More data for this Ligand-Target Pair
Target Info
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KEGG
UniProtKB/SwissProt
B.MOAD
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MCE
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PDB
3D Structure (crystal)
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Target
Kinesin-like protein KIF11
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM50382559
(ISPINESIB)
Copy SMILES
Copy InChI
Affinity Data
Ki: 2.30nM
Assay Description:
Inhibition of MT-stimulated human N-terminal His6-tagged Eg5 (1 to 368 amino acid residues) motor domain ATPase activity expressed in Escherichia col...
More data for this Ligand-Target Pair
Target Info
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MMDB
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KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
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MCE
MMDB
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Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Kinesin-like protein KIF11
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM50382559
(ISPINESIB)
Copy SMILES
Copy InChI
Affinity Data
Ki: 2.5nM
Assay Description:
Inhibition of N-terminal hexa-histidine tagged human cloned Eg5 (1 to 368 amino acids) expressed in Escherichia coli BL21 (DE3) assessed as reduction...
More data for this Ligand-Target Pair
Target Info
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MMDB
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KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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MCE
MMDB
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PC sid
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In Depth
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Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Kinesin-like protein KIF11
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM50431891
(CHEMBL2347651)
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Affinity Data
IC50: 1.20nM
Assay Description:
Inhibition of Eg5 (unknown origin)
More data for this Ligand-Target Pair
Target Info
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MMDB
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KEGG
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B.MOAD
DrugBank
antibodypedia
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CHEMBL
MCE
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PC sid
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Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Kinesin-like protein KIF11
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM50382559
(ISPINESIB)
Copy SMILES
Copy InChI
Affinity Data
IC50: 5nM
Assay Description:
Inhibition of C-terminal His-tagged microtubule-stimulated KSP motor domain (1 to 369) ATPase activity (unknown origin) preincubated for 30 mins foll...
More data for this Ligand-Target Pair
Target Info
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MMDB
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KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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MCE
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Kinesin-like protein KIF11
(Homo sapiens (Human))
Boston University
Curated by
ChEMBL
Ligand
BDBM50382559
(ISPINESIB)
Copy SMILES
Copy InChI
Affinity Data
IC50: 47nM
Assay Description:
Binding affinity against delta opioid receptor in mouse hot plate test
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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MCE
MMDB
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PC sid
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In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
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Target
Cytochrome P450 3A4
(Homo sapiens (Human))
The Beatson Institute For Cancer Research
Curated by
ChEMBL
Ligand
BDBM50382559
(ISPINESIB)
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Affinity Data
IC50: 4.10E+3nM
Assay Description:
Inhibition of CYP3A4
More data for this Ligand-Target Pair
Target Info
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Target
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human))
The Beatson Institute For Cancer Research
Curated by
ChEMBL
Ligand
BDBM50382559
(ISPINESIB)
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Affinity Data
IC50: 4.81E+3nM
Assay Description:
Inhibition of human ERG
More data for this Ligand-Target Pair
Target Info
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UniProtKB/SwissProt
UniProtKB/TrEMBL
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Target
Cytochrome P450 2C19
(Homo sapiens (Human))
The Beatson Institute For Cancer Research
Curated by
ChEMBL
Ligand
BDBM50382559
(ISPINESIB)
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Affinity Data
IC50: 2.43E+4nM
Assay Description:
Inhibition of CYP2C19
More data for this Ligand-Target Pair
Target Info
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KEGG
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Target
Cytochrome P450 2D6
(Homo sapiens (Human))
The Beatson Institute For Cancer Research
Curated by
ChEMBL
Ligand
BDBM50382559
(ISPINESIB)
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Affinity Data
IC50: >2.50E+4nM
Assay Description:
Inhibition of CYP2D6
More data for this Ligand-Target Pair
Target Info
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Target
Cytochrome P450 2C9
(Homo sapiens (Human))
The Beatson Institute For Cancer Research
Curated by
ChEMBL
Ligand
BDBM50382559
(ISPINESIB)
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Affinity Data
IC50: >2.50E+4nM
Assay Description:
Inhibition of CYP2C9
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
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MCE
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PubMed
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Target
Cytochrome P450 1A2
(Homo sapiens (Human))
The Beatson Institute For Cancer Research
Curated by
ChEMBL
Ligand
BDBM50382559
(ISPINESIB)
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Affinity Data
IC50: >2.50E+4nM
Assay Description:
Inhibition of CYP1A2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
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MCE
MMDB
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PC sid
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In Depth
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Article
PubMed
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Target
Kinesin-like protein KIFC1
(Homo sapiens (Human))
Astrazeneca
Curated by
ChEMBL
Ligand
BDBM50382559
(ISPINESIB)
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Affinity Data
IC50: >1.00E+5nM
Assay Description:
Inhibition of recombinant N-terminal His6-tagged KIFC1 (Q305-K673 aa) (unknown origin) expressed in Escherichia coli BL21 (DE3) by malachite green as...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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Ligand Info
Purchase
MCE
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI