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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
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Found
1
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Target
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human))
Amgen
Ligand
BDBM13749
((5S)-2-{[(1S)-1-(2-fluorophenyl)ethyl]amino}-5-met...)
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Affinity Data
Ki: 4nM ΔG°: -47.5kJ/mole
pH: 7.2 T: 2°C
Assay Description:
Enzyme assays were performed using purified recombinant human or mouse11beta-HSD1. The fractional conversion of cortisone to cortisol was used to det...
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