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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
6
hits in this display
Target
Melanocortin receptor 4
(Homo sapiens (Human))
Neurocrine Biosciences
Curated by
ChEMBL
Ligand
BDBM50224648
((4-(2-((S)-1-amino-2-methylpropyl)-4-methylphenyl)...)
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Affinity Data
Ki: 11nM
Assay Description:
Displacement of [125I]NDP-MSH from human MC4 receptor expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Melanocortin receptor 4
(Homo sapiens (Human))
Neurocrine Biosciences
Curated by
ChEMBL
Ligand
BDBM50224648
((4-(2-((S)-1-amino-2-methylpropyl)-4-methylphenyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 12nM
Assay Description:
Displacement of [125I]NDP-MSH from human MC4 receptor expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Melanocortin receptor 5
(Homo sapiens (Human))
Neurocrine Biosciences
Curated by
ChEMBL
Ligand
BDBM50224648
((4-(2-((S)-1-amino-2-methylpropyl)-4-methylphenyl)...)
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Affinity Data
Ki: 240nM
Assay Description:
Binding affinity at human MC5 receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Melanocortin receptor 3
(Homo sapiens (Human))
Neurocrine Biosciences
Curated by
ChEMBL
Ligand
BDBM50224648
((4-(2-((S)-1-amino-2-methylpropyl)-4-methylphenyl)...)
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Affinity Data
Ki: 1.60E+3nM
Assay Description:
Binding affinity at human MC3 receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Melanocyte-stimulating hormone receptor
(Homo sapiens (Human))
Neurocrine Biosciences
Curated by
ChEMBL
Ligand
BDBM50224648
((4-(2-((S)-1-amino-2-methylpropyl)-4-methylphenyl)...)
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Affinity Data
Ki: 3.35E+3nM
Assay Description:
Binding affinity at human MC1 receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Melanocortin receptor 4
(Homo sapiens (Human))
Neurocrine Biosciences
Curated by
ChEMBL
Ligand
BDBM50224648
((4-(2-((S)-1-amino-2-methylpropyl)-4-methylphenyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 24nM
Assay Description:
Agonist activity at human MC4 receptor expressed in CHO cells assessed as cAMP accumulation by ELISA
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI