Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50224653((4-(2-((S)-1-amino-2-methylpropyl)-4-methylphenyl)...)
Affinity DataKi:  8.60nMAssay Description:Displacement of [125I]NDP-MSH from human MC4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 5(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50224653((4-(2-((S)-1-amino-2-methylpropyl)-4-methylphenyl)...)
Affinity DataKi:  380nMAssay Description:Binding affinity at human MC5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50224653((4-(2-((S)-1-amino-2-methylpropyl)-4-methylphenyl)...)
Affinity DataKi:  1.40E+3nMAssay Description:Binding affinity at human MC3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50224653((4-(2-((S)-1-amino-2-methylpropyl)-4-methylphenyl)...)
Affinity DataIC50:  65nMAssay Description:Antagonist activity at human MC4 receptor expressed in CHO cells assessed as inhibition of alpha-MSH-stimulated of cAMP production by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed