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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
10
hits in this display
Target
Delta-type opioid receptor
(Rattus norvegicus (rat))
National Institute Of Environmental Health Sciences
Curated by
ChEMBL
Ligand
BDBM50009146
((S)-4-((S)-2-{(R)-2-[(S)-2-Amino-3-(4-hydroxy-phen...)
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Affinity Data
Ki: 8nM
Assay Description:
Inhibition of [3H]-DADLE binding to opioid receptor delta in P2 membrane preparation of rat brain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Mu-type opioid receptor
(Rattus norvegicus (rat))
National Institute Of Environmental Health Sciences
Curated by
ChEMBL
Ligand
BDBM50009146
((S)-4-((S)-2-{(R)-2-[(S)-2-Amino-3-(4-hydroxy-phen...)
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Affinity Data
Ki: 5.85E+3nM
Assay Description:
Inhibition of [3H]DAGO binding to trat brain opioid receptor mu in P2 membrane
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Delta-type opioid receptor
(MOUSE)
Vrije Universiteit Brussel
Curated by
ChEMBL
Ligand
BDBM50009146
((S)-4-((S)-2-{(R)-2-[(S)-2-Amino-3-(4-hydroxy-phen...)
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Affinity Data
IC50: 0.147nM
Assay Description:
Agonist activity at delta-opioid receptor in mouse vasa deferens assessed as inhibition of electrically induced contractions
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Delta-type opioid receptor
(MOUSE)
Vrije Universiteit Brussel
Curated by
ChEMBL
Ligand
BDBM50009146
((S)-4-((S)-2-{(R)-2-[(S)-2-Amino-3-(4-hydroxy-phen...)
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Affinity Data
IC50: 0.850nM
Assay Description:
Tested for agonist activity against delta opioid receptor mouse vas deferens
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Delta-type opioid receptor
(MOUSE)
Vrije Universiteit Brussel
Curated by
ChEMBL
Ligand
BDBM50009146
((S)-4-((S)-2-{(R)-2-[(S)-2-Amino-3-(4-hydroxy-phen...)
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Affinity Data
IC50: 1nM
Assay Description:
Antagonistic potency against thromboxane Thromboxane A2 receptor expressed as inhibition of U 46619-induced platelet aggregation in human platelet ri...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mu-type opioid receptor
(MOUSE)
Vrije Universiteit Brussel
Curated by
ChEMBL
Ligand
BDBM50009146
((S)-4-((S)-2-{(R)-2-[(S)-2-Amino-3-(4-hydroxy-phen...)
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Affinity Data
IC50: 627nM
Assay Description:
Displacement of [125I]-DAMGO from mouse Flag-tagged mu-opioid receptor expressed in HEK293 cell membranes after 60 mins by gamma counting
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mu-type opioid receptor
(GUINEA PIG)
Vrije Universiteit Brussel
Curated by
ChEMBL
Ligand
BDBM50009146
((S)-4-((S)-2-{(R)-2-[(S)-2-Amino-3-(4-hydroxy-phen...)
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Affinity Data
IC50: 854nM
Assay Description:
Agonist activity at mu-opioid receptor in guinea pig ileum assessed as inhibition of electrically induced contractions
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mu-type opioid receptor
(GUINEA PIG)
Vrije Universiteit Brussel
Curated by
ChEMBL
Ligand
BDBM50009146
((S)-4-((S)-2-{(R)-2-[(S)-2-Amino-3-(4-hydroxy-phen...)
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Affinity Data
IC50: 1.50E+4nM
Assay Description:
Tested for agonist activity against mu opioid receptor in guinea pig ileum
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mu-type opioid receptor
(Rattus norvegicus (rat))
National Institute Of Environmental Health Sciences
Curated by
ChEMBL
Ligand
BDBM50009146
((S)-4-((S)-2-{(R)-2-[(S)-2-Amino-3-(4-hydroxy-phen...)
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Copy InChI
Affinity Data
EC50: 16nM
Assay Description:
Agonist activity at rat mu-opioid receptor expressed in HEK293 cells co-expressing Rluc2-EPAC-GFP10 biosenser assessed as inhibition of forskolin-ind...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Delta-type opioid receptor
(Rattus norvegicus (rat))
National Institute Of Environmental Health Sciences
Curated by
ChEMBL
Ligand
BDBM50009146
((S)-4-((S)-2-{(R)-2-[(S)-2-Amino-3-(4-hydroxy-phen...)
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Copy InChI
Affinity Data
EC50: 0.100nM
Assay Description:
Agonist activity at rat delta-opioid receptor expressed in HEK293 cells co-expressing Rluc2-EPAC-GFP10 biosenser assessed as inhibition of forskolin-...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI