Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 8 hits in this display   

TargetNeutrophil collagenase(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50198039(CHEMBL374377 | [(R)-1-(4'-fluoro-biphenyl-4-sulfon...)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of MMP8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50198039(CHEMBL374377 | [(R)-1-(4'-fluoro-biphenyl-4-sulfon...)
Affinity DataIC50:  13nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50198039(CHEMBL374377 | [(R)-1-(4'-fluoro-biphenyl-4-sulfon...)
Affinity DataIC50:  20nMAssay Description:Inhibition of human recombinant MMP2 expressed in mouse myeloma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50198039(CHEMBL374377 | [(R)-1-(4'-fluoro-biphenyl-4-sulfon...)
Affinity DataIC50:  32nMAssay Description:Inhibition of MMP14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50198039(CHEMBL374377 | [(R)-1-(4'-fluoro-biphenyl-4-sulfon...)
Affinity DataIC50:  59nMAssay Description:Inhibition of human recombinant MMP9 expressed in mouse myeloma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50198039(CHEMBL374377 | [(R)-1-(4'-fluoro-biphenyl-4-sulfon...)
Affinity DataIC50:  150nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50198039(CHEMBL374377 | [(R)-1-(4'-fluoro-biphenyl-4-sulfon...)
Affinity DataIC50:  160nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrilysin(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50198039(CHEMBL374377 | [(R)-1-(4'-fluoro-biphenyl-4-sulfon...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of MMP7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed