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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
8
hits in this display
Target
Neutrophil collagenase
(Homo sapiens (Human))
Università
Curated by
ChEMBL
Ligand
BDBM50198039
(CHEMBL374377 | [(R)-1-(4'-fluoro-biphenyl-4-sulfon...)
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Affinity Data
IC50: 1.10nM
Assay Description:
Inhibition of MMP8
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Collagenase 3
(Homo sapiens (Human))
Università
Curated by
ChEMBL
Ligand
BDBM50198039
(CHEMBL374377 | [(R)-1-(4'-fluoro-biphenyl-4-sulfon...)
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Affinity Data
IC50: 13nM
Assay Description:
Inhibition of MMP13
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
72 kDa type IV collagenase
(Homo sapiens (Human))
Università
Curated by
ChEMBL
Ligand
BDBM50198039
(CHEMBL374377 | [(R)-1-(4'-fluoro-biphenyl-4-sulfon...)
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Affinity Data
IC50: 20nM
Assay Description:
Inhibition of human recombinant MMP2 expressed in mouse myeloma cells
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Matrix metalloproteinase-14
(Homo sapiens (Human))
Università
Curated by
ChEMBL
Ligand
BDBM50198039
(CHEMBL374377 | [(R)-1-(4'-fluoro-biphenyl-4-sulfon...)
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Affinity Data
IC50: 32nM
Assay Description:
Inhibition of MMP14
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Matrix metalloproteinase-9
(Homo sapiens (Human))
Università
Curated by
ChEMBL
Ligand
BDBM50198039
(CHEMBL374377 | [(R)-1-(4'-fluoro-biphenyl-4-sulfon...)
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Affinity Data
IC50: 59nM
Assay Description:
Inhibition of human recombinant MMP9 expressed in mouse myeloma cells
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Stromelysin-1
(Homo sapiens (Human))
Università
Curated by
ChEMBL
Ligand
BDBM50198039
(CHEMBL374377 | [(R)-1-(4'-fluoro-biphenyl-4-sulfon...)
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Affinity Data
IC50: 150nM
Assay Description:
Inhibition of MMP3
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Interstitial collagenase
(Homo sapiens (Human))
Università
Curated by
ChEMBL
Ligand
BDBM50198039
(CHEMBL374377 | [(R)-1-(4'-fluoro-biphenyl-4-sulfon...)
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Affinity Data
IC50: 160nM
Assay Description:
Inhibition of MMP1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Matrilysin
(Homo sapiens (Human))
Università
Curated by
ChEMBL
Ligand
BDBM50198039
(CHEMBL374377 | [(R)-1-(4'-fluoro-biphenyl-4-sulfon...)
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Affinity Data
IC50: 1.40E+3nM
Assay Description:
Inhibition of MMP7
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI