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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
6
hits in this display
Target
Oxysterols receptor LXR-beta
(Homo sapiens (Human))
Vitae Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50177019
(CHEMBL3813863 | US10144715, Compound 19-2)
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Affinity Data
Ki: 160nM
Assay Description:
Displacement of [3H]TO901317 from LXRbeta ligand binding domain (unknown origin) after 30 mins by liquid scintillation counting
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Oxysterols receptor LXR-beta
(Homo sapiens (Human))
Vitae Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50177019
(CHEMBL3813863 | US10144715, Compound 19-2)
Copy SMILES
Copy InChI
Affinity Data
Ki: 160nM
Assay Description:
Compounds of the invention were assessed in a competition binding assay where different concentrations of compounds were incubated with the LXR ligan...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
US Patent
Copy BDB DOI
Target
Oxysterols receptor LXR-alpha
(Homo sapiens (Human))
Vitae Pharmaceuticals
US Patent
Ligand
BDBM50177019
(CHEMBL3813863 | US10144715, Compound 19-2)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.07E+3nM
Assay Description:
Compounds of the invention were assessed in a competition binding assay where different concentrations of compounds were incubated with the LXR ligan...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
US Patent
Copy BDB DOI
Target
Oxysterols receptor LXR-alpha
(Homo sapiens (Human))
Vitae Pharmaceuticals
US Patent
Ligand
BDBM50177019
(CHEMBL3813863 | US10144715, Compound 19-2)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.07E+3nM
Assay Description:
Displacement of [3H]TO901317 from LXRalpha ligand binding domain (unknown origin) after 30 mins by liquid scintillation counting
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Oxysterols receptor LXR-beta
(Homo sapiens (Human))
Vitae Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50177019
(CHEMBL3813863 | US10144715, Compound 19-2)
Copy SMILES
Copy InChI
Affinity Data
EC50: 503nM
Assay Description:
Agonist activity at human LXRbeta ligand binding domain(155 to 460 residues) transfected in HEK293 cells after 16 hrs by Gal4-luciferase reporter gen...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Oxysterols receptor LXR-alpha
(Homo sapiens (Human))
Vitae Pharmaceuticals
US Patent
Ligand
BDBM50177019
(CHEMBL3813863 | US10144715, Compound 19-2)
Copy SMILES
Copy InChI
Affinity Data
EC50: 1.73E+3nM
Assay Description:
Agonist activity at human LXRalpha ligand binding domain(167 to 447 residues) transfected in HEK293 cells after 16 hrs by Gal4-luciferase reporter ge...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI