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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
2
hits in this display
Target
Isocitrate dehydrogenase [NADP] cytoplasmic
(Homo sapiens (Human))
Novartis
US Patent
Ligand
BDBM146136
(US8957068, 171 | US8957068, 172)
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Affinity Data
IC50: 260nM
pH: 7.4 T: 2°C
Assay Description:
Mutant IDH1 R132H catalytic activity was monitored using the quantitative liquid chromatography/mass spectrometry (LC-MS) detection of 2-HG, a produc...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
US Patent
Copy BDB DOI
Target
Isocitrate dehydrogenase [NADP] cytoplasmic
(Homo sapiens (Human))
Novartis
US Patent
Ligand
BDBM146136
(US8957068, 171 | US8957068, 172)
Copy SMILES
Copy InChI
Affinity Data
IC50: 6.16E+3nM
pH: 7.4 T: 2°C
Assay Description:
Mutant IDH1 R132H catalytic activity was monitored using the quantitative liquid chromatography/mass spectrometry (LC-MS) detection of 2-HG, a produc...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
US Patent
Copy BDB DOI