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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
1
hit in this display
Target
Isocitrate dehydrogenase [NADP] cytoplasmic
(Homo sapiens (Human))
Novartis
US Patent
Ligand
BDBM146451
(US8957068, 582)
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Affinity Data
IC50: 204nM
pH: 7.5 T: 2°C
Assay Description:
The IDH1 (R132H) mutant catalyzes the reduced form of NADP+ (NADPH) and α-ketoglutarate (α-KG) to form nicotinamide adenine dinucleotide ph...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
US Patent
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