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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetMitogen-activated protein kinase kinase kinase 12(Homo sapiens (Human))
The University Of Texas System

US Patent
LigandPNGBDBM289427((R)-1-(4-(6-amino-5-(trifluoromethoxy)pyridin-3-yl...)
Affinity DataKd:  45nMAssay Description:The DLK dissociation constants (Kd) have been determined in the KINOMEscan KdELECT Service at DiscoveRx. A fusion protein of full length of human DLK...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase 12(Homo sapiens (Human))
The University Of Texas System

US Patent
LigandPNGBDBM590004((S)-1-(4-(6-amino-5- (trifluoromethoxy)pyridin-3-y...)
Affinity DataKd:  0.290nMAssay Description:A fusion protein of full length of human DLK (amino acids 1-859) and the DNA binding domain of NFkB was expressed in transiently transfected HEK293 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetMitogen-activated protein kinase kinase kinase 12(Homo sapiens (Human))
The University Of Texas System

US Patent
LigandPNGBDBM289495(1-(4-(6-amino-5-(tri- fluoromethyl)pyridin-3- yl)-...)
Affinity DataKd:  0.110nMAssay Description:The DLK dissociation constants (Kd) have been determined in the KINOMEscan KdELECT Service at DiscoveRx. A fusion protein of full length of human DLK...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB