Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetLow affinity immunoglobulin epsilon Fc receptor(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL

LigandBDBM50069602(CHEMBL440712 | Thioacetic acid S-[(2S,3R)-3-((S)-1...)Copy SMILESCopy InChI

Affinity DataIC50:  1.00E+3nMAssay Description:Tested for inhibition against CD23 (IgE receptor) proteolysis in membranes derived from RPM18866 cells ( a human B-cell line); value ranges from 1000...More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoCHEMBLKEGGPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetInterstitial collagenase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL

LigandBDBM50069602(CHEMBL440712 | Thioacetic acid S-[(2S,3R)-3-((S)-1...)Copy SMILESCopy InChI

Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory activity of the compound towards human recombinant fibroblast collagenaseMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLKEGGPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI