Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

Target72 kDa type IV collagenase(Homo sapiens (Human))
University Medical Center Groningen

Curated by ChEMBL

LigandBDBM50035472(CHEMBL3355724)Copy SMILESCopy InChI

Affinity DataIC50:  1.45E+3nMAssay Description:Inhibition of human recombinant MMP2 catalytic domain using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 fluorogenic substrateMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetMatrix metalloproteinase-9(Homo sapiens (Human))
University Medical Center Groningen

Curated by ChEMBL

LigandBDBM50035472(CHEMBL3355724)Copy SMILESCopy InChI

Affinity DataIC50:  2.42E+3nMAssay Description:Inhibition of human recombinant MMP9 catalytic domain using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 fluorogenic substrateMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetMatrix metalloproteinase-17(Homo sapiens (Human))
University Medical Center Groningen

Curated by ChEMBL

LigandBDBM50035472(CHEMBL3355724)Copy SMILESCopy InChI

Affinity DataIC50:  3.26E+3nMAssay Description:Inhibition of human recombinant ADAM17 using Mca-PLAQAV-Dpa-RSSSR-NH2More data for this Ligand-Target Pair

Target InfoReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI