Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetSerine protease hepsin(Homo sapiens (Human))
Washington University

Curated by ChEMBL

LigandBDBM50032944(CHEMBL3356603)Copy SMILESCopy InChI

Affinity DataKi:  0.680nMAssay Description:Inhibition of recombinant hepsin (unknown origin) using Boc-QAR-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetSuppressor of tumorigenicity 14 protein(Homo sapiens (Human))
Washington University

Curated by ChEMBL

LigandBDBM50032944(CHEMBL3356603)Copy SMILESCopy InChI

Affinity DataKi:  5.80nMAssay Description:Inhibition of matriptase (unknown origin) using Boc-QAR-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetHepatocyte growth factor activator(Homo sapiens (Human))
Washington University

Curated by ChEMBL

LigandBDBM50032944(CHEMBL3356603)Copy SMILESCopy InChI

Affinity DataKi:  24nMAssay Description:Inhibition of recombinant HGFA (unknown origin) using Boc-QLR-AMC as substrate by chromogenic proteolytic assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI