Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetBeta-secretase 1(Homo sapiens (Human))
University Of Illinois At Chicago

LigandPNGBDBM16775(CHEMBL273916 | Substrate-based BACE-1 inhibitor, 1...)
Affinity DataKi:  1.13E+3nM ΔG°:  -35.3kJ/molepH: 4.5 T: 2°CAssay Description:Enzyme activities were assayed by monitoring the hydrolysis of substrate in the presence or absence of inhibitor compounds. The hydrolysis was record...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
University Of Illinois At Chicago

LigandPNGBDBM16775(CHEMBL273916 | Substrate-based BACE-1 inhibitor, 1...)
Affinity DataKi:  1.13E+3nMAssay Description:Inhibition of recombinant memapsin 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
University Of Illinois At Chicago

LigandPNGBDBM50155995(CHEMBL362324 | {(R)-1-[(S)-4-((S)-1-Benzylcarbamoy...)
Affinity DataKi:  1.13E+3nMAssay Description:Binding affinity towards Beta-secretase determined using continuum electrostatics solvationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed