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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
15
hits in this display
Target
Proteasome subunit beta type-5
(Homo sapiens (Human))
Gorlaeus Laboratories
Curated by
ChEMBL
Ligand
BDBM50307481
((S)-2-azido-N-((S)-1-((S)-1-((S)-4-methyl-1-((R)-2...)
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Affinity Data
IC50: 1nM
Assay Description:
Inhibition of 26S proteasome beta 5 using LLVY as substrate
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Proteasome subunit beta type-5
(Homo sapiens (Human))
Gorlaeus Laboratories
Curated by
ChEMBL
Ligand
BDBM50307481
((S)-2-azido-N-((S)-1-((S)-1-((S)-4-methyl-1-((R)-2...)
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Copy InChI
Affinity Data
IC50: 2.10nM
Assay Description:
Inhibition of catalytic activity of constitutive proteasome 20s subunit beta5 in human Raji cells incubated for 1 hr by BODIPY(TMR)-NC-005-VS probe b...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Proteasome subunit beta type-5
(Homo sapiens (Human))
Gorlaeus Laboratories
Curated by
ChEMBL
Ligand
BDBM50307481
((S)-2-azido-N-((S)-1-((S)-1-((S)-4-methyl-1-((R)-2...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.10nM
Assay Description:
Inhibition of catalytic activity of constitutive proteasome 20s subunit beta5 in human Raji cells incubated for 1 hr by BODIPY(TMR)-NC-005-VS probe b...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Proteasome subunit beta type-5
(Homo sapiens (Human))
Gorlaeus Laboratories
Curated by
ChEMBL
Ligand
BDBM50307481
((S)-2-azido-N-((S)-1-((S)-1-((S)-4-methyl-1-((R)-2...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 5.5nM
Assay Description:
Inhibition of catalytic activity of immunoproteasome 20s subunit beta5 in human Raji cells incubated for 1 hr by BODIPY(TMR)-NC-005-VS probe based co...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Proteasome subunit beta type-5
(Homo sapiens (Human))
Gorlaeus Laboratories
Curated by
ChEMBL
Ligand
BDBM50307481
((S)-2-azido-N-((S)-1-((S)-1-((S)-4-methyl-1-((R)-2...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 5.5nM
Assay Description:
Inhibition of catalytic activity of immunoproteasome 20s subunit beta5 in human Raji cells incubated for 1 hr by BODIPY(TMR)-NC-005-VS probe based co...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Proteasome subunit beta type-2
(Homo sapiens (Human))
Leiden Institute Of Chemistry
Curated by
ChEMBL
Ligand
BDBM50307481
((S)-2-azido-N-((S)-1-((S)-1-((S)-4-methyl-1-((R)-2...)
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Copy InChI
Affinity Data
IC50: 13nM
Assay Description:
Inhibition of catalytic activity of immunoproteasome 20s subunit beta2 in human Raji cells incubated for 1 hr by BODIPY(FL)-LU-112 probe based compet...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Proteasome subunit beta type-2
(Homo sapiens (Human))
Leiden Institute Of Chemistry
Curated by
ChEMBL
Ligand
BDBM50307481
((S)-2-azido-N-((S)-1-((S)-1-((S)-4-methyl-1-((R)-2...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 13nM
Assay Description:
Inhibition of catalytic activity of immunoproteasome 20s subunit beta2 in human Raji cells incubated for 1 hr by BODIPY(FL)-LU-112 probe based compet...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Proteasome subunit beta type-2
(Homo sapiens (Human))
Leiden Institute Of Chemistry
Curated by
ChEMBL
Ligand
BDBM50307481
((S)-2-azido-N-((S)-1-((S)-1-((S)-4-methyl-1-((R)-2...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 66nM
Assay Description:
Inhibition of catalytic activity of constitutive proteasome 20s subunit beta2 in human Raji cells incubated for 1 hr by BODIPY(FL)-LU-112 probe based...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Proteasome subunit beta type-2
(Homo sapiens (Human))
Leiden Institute Of Chemistry
Curated by
ChEMBL
Ligand
BDBM50307481
((S)-2-azido-N-((S)-1-((S)-1-((S)-4-methyl-1-((R)-2...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 67nM
Assay Description:
Inhibition of catalytic activity of constitutive proteasome 20s subunit beta2 in human Raji cells incubated for 1 hr by BODIPY(FL)-LU-112 probe based...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Proteasome subunit beta type-1
(Homo sapiens (Human))
Leiden Institute Of Chemistry
Curated by
ChEMBL
Ligand
BDBM50307481
((S)-2-azido-N-((S)-1-((S)-1-((S)-4-methyl-1-((R)-2...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 120nM
Assay Description:
Inhibition of catalytic activity of immunoproteasome 20s subunit beta1 in human Raji cells incubated for 1 hr by Cy5-NC-001 probe based competitive a...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Proteasome subunit beta type-1
(Homo sapiens (Human))
Leiden Institute Of Chemistry
Curated by
ChEMBL
Ligand
BDBM50307481
((S)-2-azido-N-((S)-1-((S)-1-((S)-4-methyl-1-((R)-2...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 123nM
Assay Description:
Inhibition of catalytic activity of immunoproteasome 20s subunit beta1 in human Raji cells incubated for 1 hr by Cy5-NC-001 probe based competitive a...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Proteasome subunit beta type-2
(Homo sapiens (Human))
Leiden Institute Of Chemistry
Curated by
ChEMBL
Ligand
BDBM50307481
((S)-2-azido-N-((S)-1-((S)-1-((S)-4-methyl-1-((R)-2...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.80E+3nM
Assay Description:
Inhibition of 26S proteasome beta 2 using RLR as substrate
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Proteasome subunit beta type-1
(Homo sapiens (Human))
Leiden Institute Of Chemistry
Curated by
ChEMBL
Ligand
BDBM50307481
((S)-2-azido-N-((S)-1-((S)-1-((S)-4-methyl-1-((R)-2...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.50E+4nM
Assay Description:
Inhibition of 26S proteasome beta 1 using nLPnLD as substrate
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Proteasome subunit beta type-1
(Homo sapiens (Human))
Leiden Institute Of Chemistry
Curated by
ChEMBL
Ligand
BDBM50307481
((S)-2-azido-N-((S)-1-((S)-1-((S)-4-methyl-1-((R)-2...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+5nM
Assay Description:
Inhibition of catalytic activity of constitutive proteasome 20s subunit beta1 in human Raji cells incubated for 1 hr by Cy5-NC-001 probe based compet...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Proteasome subunit beta type-1
(Homo sapiens (Human))
Leiden Institute Of Chemistry
Curated by
ChEMBL
Ligand
BDBM50307481
((S)-2-azido-N-((S)-1-((S)-1-((S)-4-methyl-1-((R)-2...)
Copy SMILES
Copy InChI
Affinity Data
IC50: <1.00E+5nM
Assay Description:
Inhibition of catalytic activity of constitutive proteasome 20s subunit beta1 in human Raji cells incubated for 1 hr by Cy5-NC-001 probe based compet...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI