Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50080456((S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-pheny...)
Affinity DataKi:  11.4nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in human SH-SY5Y cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50080456((S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-pheny...)
Affinity DataIC50:  26.1nMAssay Description:Agonist activity at mu opioid receptor assessed as inhibition of forskolin-induced cAMP production in human SH-SY5Y cells pretreated for 24 hrs with ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50080456((S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-pheny...)
Affinity DataIC50:  41nMAssay Description:Concentration required for 50% inhibition of [3H]-DAGO binding to mu opioid receptor in crude rat brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50080456((S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-pheny...)
Affinity DataIC50:  57.8nMAssay Description:Agonist activity at mu opioid receptor assessed as inhibition of forskolin-induced cAMP production in human SH-SY5Y cells pretreated for 24 hrs with ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed